(Q45265413)

11 December 2017

STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression (English)

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11 December 2017

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11 December 2017

Sean Diehl

3

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Hergen Spits

10

object named as

Hergen Spits

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11 December 2017

Marianne Naspetti

2

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11 December 2017

Remko Schotte

4

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11 December 2017

Maho Nagasawa

5

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11 December 2017

Erwin Wijnands

6

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11 December 2017

Ramon Gimeno

7

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11 December 2017

Florry A Vyth-Dreese

8

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11 December 2017

Bianca Blom

9

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11 December 2017

language of work or name

English

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publication date

13 February 2005

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11 December 2017

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11 December 2017

6

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11 December 2017

303-313

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11 December 2017

3

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https://scigraph.springernature.com/pub.10.1038/ni1172

11 December 2017

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cites work

Transcriptional analysis of the B cell germinal center reaction

1 reference

7 January 2021

Regulatory mechanisms that determine the development and function of plasma cells

1 reference

7 January 2021

Dissecting affinity maturation: a model explaining selection of antibody-forming cells and memory B cells in the germinal centre.

1 reference

7 January 2021

The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response

1 reference

7 January 2021

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

1 reference

7 January 2021

Suppression of signal transducer and activator of transcription 3-dependent B lymphocyte terminal differentiation by BCL-6.

1 reference

7 January 2021

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

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7 January 2021

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

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7 January 2021

Plasma cell differentiation requires the transcription factor XBP-1

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7 January 2021

Generation of memory B cells and plasma cells in vitro.

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7 January 2021

Memory B cells are biased towards terminal differentiation: a strategy that may prevent repertoire freezing

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7 January 2021

A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling

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7 January 2021

Arrested differentiation, the self-renewing memory lymphocyte, and vaccination.

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7 January 2021

The interleukin-4 receptor activates STAT5 by a mechanism that relies upon common gamma-chain

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7 January 2021

IL4 and IL13 receptors share the γc chain and activate STAT6, STAT3 and STAT5 proteins in normal human B cells

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7 January 2021

Jaks and STATs: biological implications

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7 January 2021

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

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7 January 2021

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

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7 January 2021

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

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7 January 2021

Reduced lymphomyeloid repopulating activity from adult bone marrow and fetal liver of mice lacking expression of STAT5.

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7 January 2021

Distinct effects of STAT5 activation on CD4+ and CD8+ T cell homeostasis: development of CD4+CD25+ regulatory T cells versus CD8+ memory T cells.

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7 January 2021

The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.

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7 January 2021

Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax but not the survival gene bcl-2

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7 January 2021

Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo

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7 January 2021

Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation

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7 January 2021

Long-Term Human B Cell Lines Dependent on Interleukin-4 and antibody to CD40

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7 January 2021

Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells

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7 January 2021

Characterization of the promoter region of human BCL-6 gene

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7 January 2021

Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity

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7 January 2021

Ligation of CD27 on B cells in vivo during primary immunization enhances commitment to memory B cell responses

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7 January 2021

Ligation of CD27 on murine B cells responding to T-dependent and T-independent stimuli inhibits the generation of plasma cells

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7 January 2021

Phosphatidylinositol 3-kinase and NF-kappa B/Rel are at the divergence of CD40-mediated proliferation and survival pathways

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7 January 2021

Cooperation of multiple signaling pathways in CD40-regulated gene expression in B lymphocytes

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7 January 2021

DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites

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7 January 2021

Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation

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7 January 2021

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

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7 January 2021

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

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7 January 2021

Disruption of the Bcl6 gene results in an impaired germinal center formation

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7 January 2021

Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells

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7 January 2021

Constitutive activation of STAT5 by a point mutation in the SH2 domain

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7 January 2021

Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3.

1 reference

7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

7 January 2021

Localization in situ of the co-stimulatory molecules B7.1, B7.2, CD40 and their ligands in normal human lymphoid tissue

1 reference

7 January 2021

Multiple myeloma related cells in patients undergoing autologous peripheral blood stem cell transplantation.

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7 January 2021

Identifiers

DOI

10.1038/NI1172

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Dimensions Publication ID

11 December 2017

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