(Q45271555)

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Cytochrome b mutations that modify the ubiquinol-binding pocket of the cytochrome bc1 complex and confer anti-malarial drug resistance in Saccharomyces cerevisiae

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Europe PubMed Central

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11 December 2017

Cytochrome b mutations that modify the ubiquinol-binding pocket of the cytochrome bc1 complex and confer anti-malarial drug resistance in Saccharomyces cerevisiae (English)

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Europe PubMed Central

PubMed publication ID

11 December 2017

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ChEBI release 2020-05-28

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based on heuristic

inferred from title

Saccharomyces cerevisiae

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based on heuristic

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Steven R. Meshnick

7

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Steven R Meshnick

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Europe PubMed Central

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11 December 2017

Bernard L. Trumpower

8

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Bernard L Trumpower

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11 December 2017

author name string

Jacques J Kessl

1

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Europe PubMed Central

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11 December 2017

Kevin H Ha

2

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Europe PubMed Central

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11 December 2017

Anne K Merritt

3

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Europe PubMed Central

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11 December 2017

Benjamin B Lange

4

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Europe PubMed Central

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11 December 2017

Philip Hill

5

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11 December 2017

Brigitte Meunier

6

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11 December 2017

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publication date

17 February 2005

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11 December 2017

Journal of Biological Chemistry

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11 December 2017

280

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11 December 2017

17

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11 December 2017

17142-17148

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11 December 2017

Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Efficacy of a hydroxynaphthoquinone, 566C80, in experimental Pneumocystis carinii pneumonitis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Molecular basis for atovaquone binding to the cytochrome bc1 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Atovaquone-proguanil versus chloroquine-proguanil for malaria prophylaxis in nonimmune pediatric travelers: results of an international, randomized, open-label study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Plasmodium falciparum: the effects of atovaquone resistance on respiration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Evidence of Plasmodium falciparum malaria resistant to atovaquone and proguanil hydrochloride: case reports

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Genetic confirmation of atovaquone-proguanil-resistant Plasmodium falciparum malaria acquired by a nonimmune traveler to East Africa

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Detection of atovaquone and Malarone resistance conferring mutations in Plasmodium falciparum cytochrome b gene (cytb).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Recapitulation in Saccharomyces cerevisiae of cytochrome b mutations conferring resistance to atovaquone in Pneumocystis jiroveci

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Molecular basis for atovaquone resistance in Pneumocystis jirovecii modeled in the cytochrome bc(1) complex of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Ubiquinone at center N is responsible for triphasic reduction of cytochrome b in the cytochrome bc(1) complex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Cytochrome c is released from mitochondria in a reactive oxygen species (ROS)-dependent fashion and can operate as a ROS scavenger and as a respiratory substrate in cerebellar neurons undergoing excitotoxic death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Structure of the yeast cytochrome bc1 complex with a hydroxyquinone anion Qo site inhibitor bound

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Mutations in the cytochrome b gene of Plasmodium berghei conferring resistance to atovaquone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Atovaquone - a novel broad-spectrum anti-infective drug

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

The crystal structure of mitochondrial cytochrome bc1 in complex with famoxadone: the role of aromatic-aromatic interaction in inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Human disease-related mutations in cytochrome b studied in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Multisystem disorder associated with a missense mutation in the mitochondrial cytochrome b gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Mutations in cytochrome b resulting in atovaquone resistance are associated with loss of fitness in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Replicative fitness in vivo of HIV-1 variants with multiple drug resistance-associated mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500388200

21 January 2018

Identifiers

10.1074/JBC.M500388200

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

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