(Q45294777)

English

Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease

scientific article published in January 2010

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scholarly article

1 reference

Europe PubMed Central

11 December 2017

Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease (English)

1 reference

Europe PubMed Central

11 December 2017

Huntington's disease

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inferred from title

author name string

Antonio Valencia

1

1 reference

Europe PubMed Central

11 December 2017

Patrick B Reeves

2

1 reference

Europe PubMed Central

11 December 2017

Ellen Sapp

3

1 reference

Europe PubMed Central

11 December 2017

Xueyi Li

4

1 reference

Europe PubMed Central

11 December 2017

Jonathan Alexander

5

1 reference

Europe PubMed Central

11 December 2017

Kimberly B Kegel

6

1 reference

Europe PubMed Central

11 December 2017

Kathryn Chase

7

1 reference

Europe PubMed Central

11 December 2017

Neil Aronin

8

1 reference

Europe PubMed Central

11 December 2017

Marian DiFiglia

9

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Europe PubMed Central

11 December 2017

language of work or name

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based on heuristic

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publication date

1 January 2010

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Europe PubMed Central

11 December 2017

Journal of Neuroscience Research

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Europe PubMed Central

11 December 2017

88

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Europe PubMed Central

11 December 2017

1

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Europe PubMed Central

11 December 2017

179-190

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Europe PubMed Central

11 December 2017

Critical role for lipid raft-associated Src kinases in activation of PI3K-Akt signalling

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Are there multiple pathways in the pathogenesis of Huntington's disease?

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Lipid rafts control signaling of type-1 cannabinoid receptors in neuronal cells. Implications for anandamide-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3‐induced T cell signaling

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Glycogen synthase kinase-3beta inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Spatial memory formation induces recruitment of NMDA receptor and PSD-95 to synaptic lipid rafts.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Microdomains of GPI-anchored proteins in living cells revealed by crosslinking

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Impaired regulation of brain mitochondria by extramitochondrial Ca2+ in transgenic Huntington disease rats

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Loss of cannabinoid receptors in the substantia nigra in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Flotillas of lipid rafts in transit amplifying cell-like keratinocytes

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Are cognitive changes the first symptoms of Huntington's disease? A study of gene carriers

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Lipid rafts/caveolae are essential for insulin-like growth factor-1 receptor signaling during 3T3-L1 preadipocyte differentiation induction

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Regulation of AMPA receptor localization in lipid rafts

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Flotillin-1 in the substantia nigra of the Parkinson brain and a predominant localization in catecholaminergic nerves in the rat brain

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Huntingtin associates with acidic phospholipids at the plasma membrane

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Role of GSK-3beta activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Quantitative analysis of Akt phosphorylation and activity in response to EGF and insulin treatment

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Ligand-independent activation of the EGFR by lipid raft disruption

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Glycogen synthase kinase-3beta activity plays very important roles in determining the fate of oxidative stress-inflicted neuronal cells.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

A function of huntingtin in guanine nucleotide exchange on Rab11.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Neurological abnormalities in a knock-in mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Lipid rafts regulate 2-arachidonoylglycerol metabolism and physiological activity in the striatum

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Zinc induces cell death in immortalized embryonic hippocampal cells via activation of Akt-GSK-3beta signaling

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent-resistant membrane domains

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

LTP inhibits LTD in the hippocampus via regulation of GSK3beta

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Growth factor receptors, lipid rafts and caveolae: an evolving story

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

The challenge of lipid rafts

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Epidermal growth factor receptors are localized to lipid rafts that contain a balance of inner and outer leaflet lipids: a shotgun lipidomics study

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Simvastatin reduces the association of NMDA receptors to lipid rafts: a cholesterol-mediated effect in neuroprotection.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Ethyl-EPA in Huntington disease: a double-blind, randomized, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Inhibition of spontaneous neutrophil apoptosis by parabutoporin acts independently of NADPH oxidase inhibition but by lipid raft-dependent stimulation of Akt.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Clustering of plasma membrane-bound cytochrome b5 reductase within 'lipid raft' microdomains of the neuronal plasma membrane

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Lipid rafts and signal transduction

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Expression of full-length polyglutamine-expanded Huntingtin disrupts growth factor receptor signaling in rat pheochromocytoma (PC12) cells

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Recruitment of active glycogen synthase kinase-3 into neuronal lipid rafts

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Interaction of huntingtin fragments with brain membranes--clues to early dysfunction in Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Caspase-dependent apoptosis induced by calcineurin inhibitors was prevented by glycogen synthase kinase-3 inhibitors in cultured rat cortical cells.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: roles of NADPH oxidase, mitochondria, and lipid rafts

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

GPI-anchored proteins are organized in submicron domains at the cell surface.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Line tension at lipid phase boundaries regulates formation of membrane vesicles in living cells

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function

1 reference

https://api.crossref.org/works/10.1002%2FJNR.22184

21 January 2018

Identifiers

10.1002/JNR.22184

1 reference

Europe PubMed Central

11 December 2017

1 reference

Europe PubMed Central

11 December 2017

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