(Q45297155)

11 December 2017

title

New allosteric modulators of metabotropic glutamate receptor 5 (mGluR5) found by ligand-based virtual screening (English)

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11 December 2017

author

Christopher G. Parsons

series ordinal

3

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6

Gisbert Schneider

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11 December 2017

5

Tanja Weil

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4

Petra Schneider

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11 December 2017

Steffen Renner

1

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11 December 2017

Tobias Noeske

series ordinal

2

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11 December 2017

publication date

1 April 2005

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11 December 2017

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11 December 2017

volume

6

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11 December 2017

issue

4

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11 December 2017

page(s)

620-625

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Pharmacology and functions of metabotropic glutamate receptors

11 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Comparison of support vector machine and artificial neural network systems for drug/nondrug classification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

A scoring scheme for discriminating between drugs and nondrugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Comparison of correlation vector methods for ligand-based similarity searching.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Comparison of ranking methods for virtual screening in lead-discovery programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Comparison of fingerprint-based methods for virtual screening using multiple bioactive reference structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Discovery of novel modulators of metabotropic glutamate receptor subtype-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Discovery of novel heteroarylazoles that are metabotropic glutamate subtype 5 receptor antagonists with anxiolytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

GPCR drug discovery through the exploitation of allosteric drug binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Allosteric modulators of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Mutational Analysis and Molecular Modeling of the Binding Pocket of the Metabotropic Glutamate 5 Receptor Negative Modulator 2-Methyl-6-(phenylethynyl)-pyridine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400332

21 January 2018

Identifiers

DOI

10.1002/CBIC.200400332

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11 December 2017

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