(Q45301265)

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Huntingtin regulates Ca(2+) chemotaxis and K(+)-facilitated cAMP chemotaxis, in conjunction with the monovalent cation/H(+) exchanger Nhe1, in a model developmental system: insights into its possible role in Huntington׳s disease

scientific article published on 19 August 2014

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Europe PubMed Central

PubMed publication ID

11 December 2017

Huntingtin regulates Ca(2+) chemotaxis and K(+)-facilitated cAMP chemotaxis, in conjunction with the monovalent cation/H(+) exchanger Nhe1, in a model developmental system: insights into its possible role in Huntington׳s disease (English)

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11 December 2017

Huntington's disease

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David R Soll

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11 December 2017

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Deborah Wessels

1

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Europe PubMed Central

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11 December 2017

Daniel F Lusche

2

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Europe PubMed Central

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11 December 2017

Amanda Scherer

3

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Europe PubMed Central

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11 December 2017

Spencer Kuhl

4

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11 December 2017

Michael A Myre

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11 December 2017

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19 August 2014

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11 December 2017

Developmental Biology

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11 December 2017

394

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11 December 2017

1

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Europe PubMed Central

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11 December 2017

24-38

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Europe PubMed Central

PubMed publication ID

11 December 2017

Signal Propagation during Aggregation in the Slime Mould Dictyostelium discoideum

1 reference

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A high-affinity plasma membrane Ca2+-ATPase in Dictyostelium discoideum: its relation to cAMP-induced Ca2+ fluxes

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Normal huntingtin function: an alternative approach to Huntington's disease

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Actin polymerization and pseudopod extension during amoeboid chemotaxis

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Forming the cell rear first: breaking cell symmetry to trigger directed cell migration.

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Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

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Actin activation of myosin heavy chain kinase A in Dictyostelium: a biochemical mechanism for the spatial regulation of myosin II filament disassembly

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Calcium mobilization stimulates Dictyostelium discoideum shear-flow-induced cell motility.

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Cell behavior in Dictyostelium discoideum: preaggregation response to localized cyclic AMP pulses

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Neuronal Ca(2+) dyshomeostasis in Huntington disease.

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Huntington's disease

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Relationship of pseudopod extension to chemotactic hormone-induced actin polymerization in amoeboid cells

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Targeting glial cells to elucidate the pathogenesis of Huntington's disease.

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Huntington's disease: from pathology and genetics to potential therapies

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Gradient sensing during chemotaxis

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Huntingtin interacting proteins are genetic modifiers of neurodegeneration

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A chemoattractant receptor controls development in Dictyostelium discoideum

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Dictyostelium myosin heavy chain kinase A regulates myosin localization during growth and development

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The acrasin activity of adenosine-3',5'-cyclic phosphate

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Mechano-chemical signaling maintains the rapid movement of Dictyostelium cells

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Nhe1 is essential for potassium but not calcium facilitation of cell motility and the monovalent cation requirement for chemotactic orientation in Dictyostelium discoideum

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The effects of extracellular calcium on motility, pseudopod and uropod formation, chemotaxis, and the cortical localization of myosin II in Dictyostelium discoideum

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The IplA Ca2+ channel of Dictyostelium discoideum is necessary for chemotaxis mediated through Ca2+, but not through cAMP, and has a fundamental role in natural aggregation

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Calcium and neurodegeneration

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Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor.

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Simple system--substantial share: the use of Dictyostelium in cell biology and molecular medicine

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Biochemical characterization of a Dictyostelium myosin II heavy-chain phosphatase that promotes filament assembly

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Clues to γ-secretase, huntingtin and Hirano body normal function using the model organism Dictyostelium discoideum

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Deficiency of huntingtin has pleiotropic effects in the social amoeba Dictyostelium discoideum

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Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

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A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis

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Ca2+ regulation in the absence of the iplA gene product in Dictyostelium discoideum

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Ca2+ chemotaxis inDictyostelium discoideum

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How a cell crawls and the role of cortical myosin II

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Recruitment of a myosin heavy chain kinase to actin-rich protrusions in Dictyostelium

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10.1016/J.YDBIO.2014.08.009

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Europe PubMed Central

PubMed publication ID

11 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

ResearchGate publication ID

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