(Q45302284)

11 December 2017

Huntingtin's critical cleavage (English)

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11 December 2017

Huda Y Zoghbi

2

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author name string

John D Fryer

series ordinal

1

1 reference

PubMed ID

16936769

11 December 2017

language of work or name

English

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publication date

1 September 2006

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11 December 2017

1 reference

11 December 2017

9

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11 December 2017

9

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11 December 2017

1088-1089

1 reference

https://scigraph.springernature.com/pub.10.1038/nn0906-1088

11 December 2017

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cites work

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Diseases of unstable repeat expansion: mechanisms and common principles

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

SUMO modification of Huntingtin and Huntington's disease pathology

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis.

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Wild-type huntingtin protects neurons from excitotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FNN0906-1088

7 January 2021

Identifiers

DOI

10.1038/NN0906-1088

1 reference

PubMed ID

16936769

Dimensions Publication ID

11 December 2017

0 references

1 reference

PubMed ID

16936769