(Q45305379)

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Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators

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Europe PubMed Central

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11 December 2017

Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators (English)

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Europe PubMed Central

PubMed publication ID

11 December 2017

9

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11 December 2017

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Chiara Zuccato

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object named as

Marta Valenza

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author name string

Dorotea Rigamonti

1

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11 December 2017

Daniele Bolognini

2

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11 December 2017

Cesare Mutti

3

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Europe PubMed Central

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11 December 2017

Marzia Tartari

5

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Europe PubMed Central

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11 December 2017

Francesco Sola

6

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11 December 2017

Aleksey G Kazantsev

8

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11 December 2017

language of work or name

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publication date

12 June 2007

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11 December 2017

Journal of Biological Chemistry

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11 December 2017

282

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11 December 2017

34

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11 December 2017

24554-24562

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11 December 2017

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Huntington's disease: prospects for neuroprotective therapy 10 years after the discovery of the causative genetic mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Emerging chemotherapeutic strategies for Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

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Modeling Huntington's disease in cells, flies, and mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Normal huntingtin function: an alternative approach to Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

A common silencer element in the SCG10 and type II Na+ channel genes binds a factor present in nonneuronal cells but not in neuronal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Neuron-specific expression of the rat brain type II sodium channel gene is directed by upstream regulatory elements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

AAV-mediated gene delivery of BDNF or GDNF is neuroprotective in a model of Huntington disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Interaction of the repressor element 1-silencing transcription factor (REST) with target genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Transcriptional repression by neuron-restrictive silencer factor is mediated via the Sin3-histone deacetylase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Corepressor-dependent silencing of chromosomal regions encoding neuronal genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Neurotrophins and depression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A): a potent and selective corticotrophin-releasing factor(1) receptor antagonist. I. Bi

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Pharmacological characterization of a novel nonpeptide antagonist radioligand, (+/-)-N-[2-methyl-4-methoxyphenyl]-1-(1-(methoxymethyl) propyl)-6-methyl-1H-1,2,3-triazolo[4,5-c]pyridin-4-amine ([3H]SN003) for corticotropin-releasing factor1 receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

The CRF1 receptor antagonist, antalarmin, reverses isolation-induced up-regulation of dopamine D2 receptors in the amygdala and nucleus accumbens of fawn-hooded rats.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Identification of brain-derived neurotrophic factor promoter regions mediating tissue-specific, axotomy-, and neuronal activity-induced expression in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

Generation and characterization of embryonic striatal conditionally immortalized ST14A cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609885200

21 January 2018

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M609885200

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

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