(Q39333674)

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Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.

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1 January 2020

Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease (English)

1 reference

Europe PubMed Central

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1 January 2020

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Huntington's disease

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11

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1 January 2020

1

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1 January 2020

4

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1 January 2020

Marcy E. MacDonald

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Marcy MacDonald

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1 January 2020

8

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Elisa Fossale

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1 January 2020

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Noel Buckley

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Nikolai Belyaev

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1 January 2020

Paola Conforti

3

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1 January 2020

Marzia Tartari

5

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1 January 2020

Evangelia Papadimou

6

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1 January 2020

Scott Zeitlin

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1 January 2020

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publication date

1 June 2007

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1 January 2020

Journal of Neuroscience

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1 January 2020

27

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1 January 2020

6972-6983

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1 January 2020

26

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1 January 2020

Neuron-specific splicing of zinc finger transcription factor REST/NRSF/XBR is frequent in neuroblastomas and conserved in human, mouse and rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of normal huntingtin function: new developments in Huntington's disease research

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant protein in Huntington disease is resistant to proteolysis in affected brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient in nervous system-specific carbohydrate epitope HNK-1 exhibit impaired synaptic plasticity and spatial learning

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional abnormalities in Huntington disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-1,3-Glucuronyltransferase-1 gene implicated as a candidate for a schizophrenia-like psychosis through molecular analysis of a balanced translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of wild-type huntingtin in mouse models of neurologic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct RE-1 silencing transcription factor-containing complexes interact with different target genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of the repressor element 1-silencing transcription factor (REST) with target genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stannin, a protein that localizes to the mitochondria and sensitizes NIH-3T3 cells to trimethyltin and dimethyltin toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of wild-type huntingtin influences motor dysfunction and survival in the YAC128 mouse model of Huntington disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression in Huntington's disease skeletal muscle: a potential biomarker

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of GnRH and infertility in the R6/2 mouse model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal huntingtin function: an alternative approach to Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional and cellular gene expression changes in human Huntington's disease brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of brain-derived neurotrophic factor in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential loss of striatal projection neurons in Huntington disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ornithine aminotransferase in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of the mouse Huntington's disease gene homolog Hdh

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal expression of zinc finger transcription factor REST/NRSF/XBR gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/17596446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4278-06.2007

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17596446%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17596446%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17596446%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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