(Q45306738)

11 December 2017

Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load (English)

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11 December 2017

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2

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11 December 2017

Austen J Milnerwood

1

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PubMed ID

17947312

11 December 2017

language of work or name

English

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publication date

18 October 2007

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11 December 2017

Journal of Physiology

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11 December 2017

585

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11 December 2017

817-831

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11 December 2017

Pt 3

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Altered cortical glutamate receptor function in the R6/2 model of Huntington's disease

11 December 2017

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Role of excitotoxicity in human neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Psychiatric symptoms in neurologically asymptomatic Huntington's disease gene carriers: a comparison with gene negative at risk subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

A synaptic model of memory: long-term potentiation in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

NMDA receptor function in mouse models of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

The corticostriatal pathway in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

The chemical biology of clinically tolerated NMDA receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

21 January 2018

Excitotoxic cell death

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Abnormal cortical synaptic plasticity in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Aberrant cortical synaptic plasticity and dopaminergic dysfunction in a mouse model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Early changes in Huntington's disease patient brains involve alterations in cytoskeletal and synaptic elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

It could be habit forming: drugs of abuse and striatal synaptic plasticity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Synaptic vesicles recycling spontaneously and during activity belong to the same vesicle pool.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Pro-survival signalling from the NMDA receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Coupling of extrasynaptic NMDA receptors to a CREB shut-off pathway is developmentally regulated

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Mechanisms underlying developmental speeding in AMPA-EPSC decay time at the calyx of Held.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Dopamine modulation of state-dependent endocannabinoid release and long-term depression in the striatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Huntington's disease gene: regional and cellular expression in brain of normal and affected individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Visual object and visuospatial cognition in Huntington's disease: implications for information processing in corticostriatal circuits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Huntingtin-protein interactions and the pathogenesis of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Enhanced striatal NR2B-containing N-methyl-D-aspartate receptor-mediated synaptic currents in a mouse model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Long-term potentiation: outstanding questions and attempted synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Glutamate-based therapeutic approaches: ampakines

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Early development of aberrant synaptic plasticity in a mouse model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Expression mechanisms underlying long-term potentiation: a postsynaptic view

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Linking endocytic cargo to clathrin: structural and functional insights into coated vesicle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Preparing for preventive clinical trials: the Predict-HD study

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Brain structure in preclinical Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Molecular mechanisms associated with long-term consolidation of the NMDA signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

The synaptic localization of NR2B-containing NMDA receptors is controlled by interactions with PDZ proteins and AP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Altered receptor trafficking in Huntingtin Interacting Protein 1-transformed cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Disruption of endocannabinoid release and striatal long-term depression by postsynaptic blockade of endocannabinoid membrane transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Induction of striatal long-term synaptic depression by moderate frequency activation of cortical afferents in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

An isolated pool of vesicles recycles at rest and drives spontaneous neurotransmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

NR2B-containing receptors mediate cross talk among hippocampal synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Verbal episodic memory declines prior to diagnosis in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Alterations in N-methyl-D-aspartate receptor sensitivity and magnesium blockade occur early in development in the R6/2 mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

The synaptic vesicle cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

LTP and adaptation to inactivity: overlapping mechanisms and implications for metaplasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Facilitation, augmentation and potentiation at central synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Impaired synaptic plasticity in mice carrying the Huntington's disease mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

NMDA/AMPA ratio impacts state transitions and entrainment to oscillations in a computational model of the nucleus accumbens medium spiny projection neuron.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Altered corticostriatal neurotransmission and modulation in dopamine transporter knock-down mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

The origin of quantal size variation: vesicular glutamate concentration plays a significant role.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Glutamate receptor expression in rat striatum: effect of deafferentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Mutant huntingtin enhances excitotoxic cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Minis: whence and wherefore?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2007.142448

Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors

21 January 2018

1 reference

12 December 2020

The glutamate receptor ion channels

1 reference

12 December 2020

Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase

1 reference

12 December 2020

Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease

1 reference

12 December 2020

D1 dopamine receptor-induced cyclic AMP-dependent protein kinase phosphorylation and potentiation of striatal glutamate receptors

1 reference

12 December 2020

Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.

1 reference

12 December 2020

Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease

1 reference

12 December 2020

Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation.

1 reference

12 December 2020

Differential modulation of AMPA receptors by cyclothiazide in two types of striatal neurons

1 reference

12 December 2020

Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo

1 reference

12 December 2020

Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice

1 reference

12 December 2020

Postsynaptic endocannabinoid release is critical to long-term depression in the striatum

1 reference

12 December 2020

Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease.

1 reference

12 December 2020

Changes in the statistics of transmitter release during facilitation

1 reference

12 December 2020

Neuropathological classification of Huntington's disease

1 reference

12 December 2020

Trinucleotide repeat length instability and age of onset in Huntington's disease

1 reference

12 December 2020

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

12 December 2020

CAG expansion affects the expression of mutant Huntingtin in the Huntington's disease brain

1 reference

12 December 2020

The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons.

1 reference

12 December 2020

10.1113/JPHYSIOL.2007.142448

Identifiers

DOI

1 reference

11 December 2017

0 references

1 reference

PubMed ID

17947312