(Q45309583)

12 December 2017

The histone-deacetylase inhibitor SAHA potentiates proapoptotic effects of 5-fluorouracil and irinotecan in hepatoma cells (English)

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12 December 2017

hepatocellular carcinoma

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1

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12 December 2017

Abdullah Alajati

2

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12 December 2017

Marion Ganslmayer

3

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12 December 2017

Steffen Zopf

4

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12 December 2017

Mike Lüders

5

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12 December 2017

Daniel Neureiter

6

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12 December 2017

Eckhart G Hahn

7

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12 December 2017

Detlef Schuppan

8

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12 December 2017

Christoph Herold

9

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12 December 2017

8 March 2005

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Journal of Cancer Research and Clinical Oncology

12 December 2017

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12 December 2017

131

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12 December 2017

6

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12 December 2017

385-394

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https://scigraph.springernature.com/pub.10.1007/s00432-004-0664-6

12 December 2017

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cites work

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

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12 December 2020

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

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12 December 2020

Clinical pharmacology of 5-fluorouracil

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12 December 2020

The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells

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12 December 2020

The National Cancer Data Base Report on treatment patterns for hepatocellular carcinomas: improved survival of surgically resected patients, 1985-1996.

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12 December 2020

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo

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12 December 2020

Synergistic antitumor activity of irinotecan in combination with 5-fluorouracil in rats bearing advanced colorectal cancer: role of drug sequence and dose.

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12 December 2020

Biochemistry of multidrug resistance mediated by the multidrug transporter

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12 December 2020

Cellular interactions of 5-fluorouracil and the camptothecin analogue CPT-11 (irinotecan) in a human colorectal carcinoma cell line

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12 December 2020

Hepatocellular carcinoma

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12 December 2020

Oral eniluracil/5-fluorouracil in patients with inoperable hepatocellular carcinoma

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12 December 2020

Combination of irinotecan (CPT11) and 5-fluorouracil with an analysis of cellular determinants of drug activity

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12 December 2020

Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

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12 December 2020

Irinotecan (CPT-11): recent developments and future directions--colorectal cancer and beyond

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12 December 2020

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

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12 December 2020

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

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12 December 2020

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

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12 December 2020

Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis

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12 December 2020

Non-surgical treatment of hepatocellular carcinoma

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12 December 2020

Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

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12 December 2020

A phase II study of irinotecan in patients with advanced hepatocellular carcinoma

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12 December 2020

Modulation of glucuronidation of SN-38, the active metabolite of irinotecan, by valproic acid and phenobarbital

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12 December 2020

Review article: Overview of medical treatments in unresectable hepatocellular carcinoma--an impossible meta-analysis?

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12 December 2020

JC-1: a very sensitive fluorescent probe to test Pgp activity in adult acute myeloid leukemia.

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12 December 2020

Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity

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12 December 2020

Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA).

1 reference

12 December 2020

Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression

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12 December 2020

Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells

1 reference

12 December 2020

Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line

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12 December 2020

Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

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12 December 2020

Sequence-dependent activity of the irinotecan-5FU combination in human colon-cancer model HT-29 in vitro and in vivo

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12 December 2020

Management of hepatocellular carcinoma

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12 December 2020

5-Fluorouracil: mechanisms of action and clinical strategies

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12 December 2020

10.1007/S00432-004-0664-6

Identifiers

DOI

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Dimensions Publication ID

12 December 2017

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