(Q45317986)

English

Negative regulation of FGFR2 signaling

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5654727)

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Statements

biological pathway

1 reference

8 July 2022

Signaling by FGFR2

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5654727

1 reference

8 July 2022

Spry regulation of FGF signaling

1 reference

8 July 2022

Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2

1 reference

8 July 2022

p-CBL:GRB2 binds p-FRS2:activated FGFR2

1 reference

8 July 2022

CBL ubiquitinates FRS2 and FGFR2

1 reference

8 July 2022

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

1 reference

8 July 2022

FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.

1 reference

8 July 2022

Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function

1 reference

8 July 2022

Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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