(Q37152909)

18 August 2017

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title

Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins (English)

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18 August 2017

Noriko Gotoh

1

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18 August 2017

publication date

29 April 2008

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18 August 2017

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18 August 2017

volume

99

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18 August 2017

issue

7

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18 August 2017

page(s)

1319-1325

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Cell signaling by receptor tyrosine kinases

18 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Signaling through scaffold, anchoring, and adaptor proteins

21 January 2018

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Dynamic control of signaling by modular adaptor proteins

21 January 2018

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The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors

21 January 2018

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The "Gab" in signal transduction.

21 January 2018

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Inhibitory adaptors in lymphocytes

21 January 2018

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SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

21 January 2018

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A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1

21 January 2018

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SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Developmental expression patterns of the signaling adapters FRS-2 and FRS-3 during early embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

SNT-1/FRS2alpha physically interacts with Laloo and mediates mesoderm induction by fibroblast growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Xenopus FRS2 is involved in early embryogenesis in cooperation with the Src family kinase Laloo

21 January 2018

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Docking protein SNT1 is a critical mediator of fibroblast growth factor signaling during Xenopus embryonic development.

21 January 2018

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Cellular signaling by fibroblast growth factor receptors

21 January 2018

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FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

The RET proto-oncogene: a molecular therapeutic target in thyroid cancer

21 January 2018

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Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction

21 January 2018

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Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

21 January 2018

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ALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiation

21 January 2018

1 reference

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The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

EGFR and FGFR signaling through FRS2 is subject to negative feedback control by ERK1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Structural basis of SNT PTB domain interactions with distinct neurotrophic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Identification of multiple SNT-binding sites on NPM-ALK oncoprotein and their involvement in cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

FRS2 PTB domain conformation regulates interactions with divergent neurotrophic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

SNT-2 interacts with ERK2 and negatively regulates ERK2 signaling in response to EGF stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Direct interaction of Rnd1 with FRS2 beta regulates Rnd1-induced down-regulation of RhoA activity and is involved in fibroblast growth factor-induced neurite outgrowth in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

The role of Shp2 (PTPN11) in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Direct cell cycle regulation by the fibroblast growth factor receptor (FGFR) kinase through phosphorylation-dependent release of Cks1 from FGFR substrate 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Sprouty and cancer: the first terms report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

FRS2-dependent SRC activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

mSprouty2 inhibits FGF10-activated MAP kinase by differentially binding to upstream target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

The docking protein FRS2alpha is an essential component of multiple fibroblast growth factor responses during early mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

FRS2 alpha 2F/2F mice lack carotid body and exhibit abnormalities of the superior cervical sympathetic ganglion and carotid sinus nerve.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Fibroblast growth factors in cancer: therapeutic possibilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Fibroblast growth factor signaling in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

Expression of the SNT-1/FRS2 phosphotyrosine binding domain inhibits activation of MAP kinase and PI3-kinase pathways and antiestrogen resistant growth induced by FGF-1 in human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00840.X

10.1111/J.1349-7006.2008.00840.X

21 January 2018

Identifiers

DOI

1 reference

18 August 2017

1 reference