(Q50297602)

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Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5654562)

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1 reference

8 July 2022

Negative regulation of FGFR2 signaling

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-5654562

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8 July 2022

Activated FGFR2:FRS2 [plasma membrane]

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8 July 2022

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8 July 2022

Activated FGFR2:p-8T-FRS2 [plasma membrane]

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8 July 2022

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8 July 2022

p-T,Y MAPK dimers [cytosol]

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8 July 2022

EGFR and FGFR signaling through FRS2 is subject to negative feedback control by ERK1/2.

1 reference

8 July 2022

FGF-receptor substrate 2 functions as a molecular sensor integrating external regulatory signals into the FGF pathway

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8 July 2022

The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors

1 reference

8 July 2022

Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q50297602)

Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2

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