(Q45346605)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Mode of action of trabectedin in myxoid liposarcomas (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Sarah Uboldi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Elena Tamborini

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Paolo Giovanni Casali

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Roberta Sanfilippo

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Alessandro Gronchi

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Maurizio D'Incalci

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Roberta Frapolli

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Sergio Marchini

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Luca Beltrame

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Silvia Brich

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

S Di Giandomenico

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

S A Licandro

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

V Mauro

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

S Pilotti

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

F Grosso

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

R Mantovani

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

R Gatta

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

C M Galmarini

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

J M F Sousa-Faro

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

English

0 references

publication date

11 November 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

5201-5210

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: liposarcoma

29 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Functional mapping of receptor tyrosine kinases in myxoid liposarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Transcriptional activation by TAL1 and FUS-CHOP proteins expressed in acute malignancies as a result of chromosomal abnormalities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

CCAAT/enhancer-binding proteins: structure, function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Human translocation liposarcoma-CCAAT/enhancer binding protein (C/EBP) homologous protein (TLS-CHOP) oncoprotein prevents adipocyte differentiation by directly interfering with C/EBPbeta function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

The chimeric FUS/TLS-CHOP fusion protein specifically induces liposarcomas in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Myxoid tumours of soft tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Detection of myxoid liposarcoma-associated FUS-DDIT3 rearrangement variants including a newly identified breakpoint using an optimized RT-PCR assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Relevance of translocation type in myxoid liposarcoma and identification of a novel EWSR1-DDIT3 fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Differential cytostatic and apoptotic effects of ecteinascidin-743 in cancer cells. Transcription-dependent cell cycle arrest and transcription-independent JNK and mitochondrial mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

In vitro antitumor activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Preclinical and clinical results with the natural marine product ET-743

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Ecteinascidin 743: a minor groove alkylator that bends DNA toward the major groove

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

A review of trabectedin (ET-743): a unique mechanism of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Sensitivity of CHO mutant cell lines with specific defects in nucleotide excision repair to different anti-cancer agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Role of homologous recombination in trabectedin-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Selective effects of the anticancer drug Yondelis (ET-743) on cell-cycle promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Trabectedin in myxoid liposarcomas (MLS): a long-term analysis of a single-institution series.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

PPARγ agonists enhance ET-743-induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Novel models of myxoid liposarcoma xenografts mimicking the biological and pharmacologic features of human tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

DNA and its associated processes as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Sequence-specific DNA recognition by polyamides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Effects of minor groove binding drugs on the interaction of TATA box binding protein and TFIIA with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Adipocyte differentiation from the inside out

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and pre-operative radiation therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

High-Risk Human Papillomavirus Affects Prognosis in Patients With Surgically Treated Oropharyngeal Squamous Cell Carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Temperature-dependent localization of TLS-CHOP to splicing factor compartments

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.462

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.462

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 February 2020

1047744564

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213580%20AND%20SRC:MED&resulttype=core&format=json