(Q45347471)

13 December 2017

title

Evidence for a crucial modulating role of the sodium channel in the QTc prolongation related to antipsychotics (English)

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13 December 2017

Jordi S Silvestre

1

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13 December 2017

Michael F O'Neill

series ordinal

2

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13 December 2017

Josep R Prous

series ordinal

3

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13 December 2017

language of work or name

English

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publication date

10 December 2013

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Journal of Psychopharmacology

13 December 2017

published in

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13 December 2017

volume

28

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13 December 2017

issue

4

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13 December 2017

page(s)

329-340

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Effects of newer atypical antipsychotics on autonomic neurocardiac function: a comparison between amisulpride, olanzapine, sertindole, and clozapine

13 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

The role of sodium channel current in modulating transmural dispersion of repolarization and arrhythmogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Assessing predictors of drug-induced torsade de pointes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Drugs that prolong QT interval as an unwanted effect: assessing their likelihood of inducing hazardous cardiac dysrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Validation of a [3H]astemizole binding assay in HEK293 cells expressing HERG K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Effects of antipsychotic drugs on I(to), I (Na), I (sus), I (K1), and hERG: QT prolongation, structure activity relationship, and network analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Organising evidence on QT prolongation and occurrence of Torsades de Pointes with non-antiarrhythmic drugs: a call for consensus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Variability of heart rate correction methods for the QT interval

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Three-dimensional quantitative structure-activity relationship for inhibition of human ether-a-go-go-related gene potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

The impact of varying autonomic states on the dynamic beat-to-beat QT-RR and QT-TQ interval relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

An evaluation of hERG current assay performance: Translating preclinical safety studies to clinical QT prolongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

The 'overly-sensitive' heart: sodium channel block and QRS interval prolongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Current concepts in the mechanisms and management of drug-induced QT prolongation and torsade de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Antipsychotic-related QTc prolongation, torsade de pointes and sudden death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

On the relationship between block of the cardiac Na⁺ channel and drug-induced prolongation of the QRS complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

21 January 2018

Drug-induced arrhythmia

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Modulation of the late sodium current by ATX-II and ranolazine affects the reverse use-dependence and proarrhythmic liability of IKr blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Vagal control of the heart: central serotonergic (5-HT) mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Drug-induced long QT and torsade de pointes: recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Central 5-HT7 receptors are critical for reflex activation of cardiac vagal drive in anaesthetized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Drug-induced arrhythmias and sudden cardiac death: implications for the pharmaceutical industry

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Timing of new black box warnings and withdrawals for prescription medications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

The utility of hERG and repolarization assays in evaluating delayed cardiac repolarization: influence of multi-channel block

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Electrocardiographic reference ranges derived from 79,743 ambulatory subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Assessing QT interval prolongation and its associated risks with antipsychotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Drug-induced prolongation of the QT interval

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Key clinical considerations for demonstrating the utility of preclinical models to predict clinical drug-induced torsades de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Update on the evaluation of a new drug for effects on cardiac repolarization in humans: issues in early drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Molecular mechanisms of adrenergic stimulation in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Antipsychotic drug doses and neuroleptic/dopamine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias. Long QT syndrome and Brugada syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Research on adverse drug events. I. Muscarinic M3 receptor binding affinity could predict the risk of antipsychotics to induce type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Comparative evaluation of hERG potassium channel blockade by antipsychotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Effect of adrenergic stimulation on action potential duration restitution in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Prevalence of QT interval prolongation in patients admitted to cardiac care units and frequency of subsequent administration of QT interval-prolonging drugs: a prospective, observational study in a large urban academic medical center in the US.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Atypical antipsychotics: from potassium channels to torsade de pointes and sudden death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Long QT syndromes and torsade de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Psychotropic drugs, cardiac arrhythmia, and sudden death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

Inhibition of late (sustained/ persistent) sodium current: a potential drug target to reduce intracellular sodium-dependent calcium overload and its detrimental effects on cardiomyocyte function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

The QT interval and torsade de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0269881113515064

21 January 2018

Identifiers

DOI

10.1177/0269881113515064

1 reference

13 December 2017

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