(Q45370513)

13 December 2017

Correction of a pathogenic gene mutation in human embryos (English)

1 reference

gene editing of human embryos

13 December 2017

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author

Juan Carlos Izpisúa Belmonte

27

object named as

Juan Carlos Izpisua Belmonte

1 reference

13 December 2017

29

Jin-Soo Kim

1 reference

13 December 2017

Hong Ma

1

1 reference

13 December 2017

Nuria Marti-Gutierrez

2

1 reference

13 December 2017

Sang-Wook Park

3

1 reference

13 December 2017

Jun Wu

4

1 reference

13 December 2017

Yeonmi Lee

5

1 reference

13 December 2017

Keiichiro Suzuki

6

1 reference

13 December 2017

Amy Koski

7

1 reference

13 December 2017

Dongmei Ji

8

1 reference

13 December 2017

Tomonari Hayama

9

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13 December 2017

Riffat Ahmed

10

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13 December 2017

Hayley Darby

11

1 reference

13 December 2017

Crystal Van Dyken

12

1 reference

13 December 2017

Ying Li

13

1 reference

13 December 2017

Eunju Kang

14

1 reference

13 December 2017

A-Reum Park

15

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13 December 2017

Daesik Kim

16

1 reference

13 December 2017

Sang-Tae Kim

17

1 reference

13 December 2017

Jianhui Gong

18

1 reference

13 December 2017

Ying Gu

19

1 reference

13 December 2017

Xun Xu

20

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13 December 2017

David Battaglia

21

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13 December 2017

Sacha A Krieg

22

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13 December 2017

David M Lee

23

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13 December 2017

Diana H Wu

24

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13 December 2017

Don P Wolf

25

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13 December 2017

Stephen B Heitner

26

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13 December 2017

Paula Amato

28

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13 December 2017

Sanjiv Kaul

30

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13 December 2017

Shoukhrat Mitalipov

31

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13 December 2017

language of work or name

English

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publication date

2 August 2017

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13 December 2017

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13 December 2017

548

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13 December 2017

7668

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13 December 2017

413-419

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https://scigraph.springernature.com/pub.10.1038/nature23305

13 December 2017

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cites work

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

A common MYBPC3 (cardiac myosin binding protein C) variant associated with cardiomyopathies in South Asia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary Artery Risk Development in (Young) Adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: mechanisms and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Development and applications of CRISPR-Cas9 for genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

RNA-guided human genome engineering via Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Correction of a genetic disease in mouse via use of CRISPR-Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Targeted genome editing in primate embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

A guide to genome engineering with programmable nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

The timing of pronuclear formation, DNA synthesis and cleavage in the human 1-cell embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Asymmetric parental genome engineering by Cas9 during mouse meiotic exit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

DNA targeting specificity of RNA-guided Cas9 nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Integrative genomics viewer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Sequence logos: a new way to display consensus sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

BatMis: a fast algorithm for k-mismatch mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Hypersensitivity of primordial germ cells to compromised replication-associated DNA repair involves ATM-p53-p21 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

The Landscape of Mouse Meiotic Double-Strand Break Formation, Processing, and Repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

CRISPR/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Mitosis inhibits DNA double-strand break repair to guard against telomere fusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Towards germline gene therapy of inherited mitochondrial diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Cas-analyzer: an online tool for assessing genome editing results using NGS data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Isaac: ultra-fast whole-genome secondary analysis on Illumina sequencing platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

inferred from DOI database lookup

7 January 2021

based on heuristic

Genotyping with CRISPR-Cas-derived RNA-guided endonucleases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23305

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE23305

1 reference

13 December 2017

1 reference