(Q45388639)

English

Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS?

scientific article published on 10 July 2012

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 December 2017

Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS? (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

amyotrophic lateral sclerosis

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based on heuristic

inferred from title

Reinhard Dengler

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object named as

Reinhard Dengler

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Europe PubMed Central

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14 December 2017

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object named as

Susanne Petri

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object named as

Sonja Körner

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object named as

Nadine Thau

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Sebastian Böselt

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object named as

Sebastian Böselt

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14 December 2017

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Klaus Jan Rath

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14 December 2017

publication date

10 July 2012

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14 December 2017

Neurodegenerative Diseases

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11

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141-152

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14 December 2017

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1159%2F000338048

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Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords--screening by molecular indexing and subsequent cDNA microarray analysis

1 reference

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Additive neuroprotective effects of a histone deacetylase inhibitor and a catalytic antioxidant in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

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Histone deacetylation and motor neuron degeneration

1 reference

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Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

1 reference

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Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice

1 reference

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Distribution of histone deacetylases 1-11 in the rat brain

1 reference

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21 January 2018

Differential histone deacetylase mRNA expression patterns in amyotrophic lateral sclerosis

1 reference

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Paths of convergence: sirtuins in aging and neurodegeneration

1 reference

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The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

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SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

1 reference

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Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease

1 reference

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Distribution of GABAA receptor subunit mRNAs in rat lumbar spinal cord

1 reference

https://api.crossref.org/works/10.1159%2F000338048

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Distribution of GABAAReceptor mRNA in the Motor Cortex of ALS Patients

1 reference

https://api.crossref.org/works/10.1159%2F000338048

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Microtubule deacetylases, SirT2 and HDAC6, in the nervous system

1 reference

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21 January 2018

The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility

1 reference

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21 January 2018

Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin

1 reference

https://api.crossref.org/works/10.1159%2F000338048

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Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

1 reference

https://api.crossref.org/works/10.1159%2F000338048

21 January 2018

Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1

1 reference

https://api.crossref.org/works/10.1159%2F000338048

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SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons

1 reference

https://api.crossref.org/works/10.1159%2F000338048

21 January 2018

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

1 reference

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21 January 2018

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

1 reference

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21 January 2018

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

https://api.crossref.org/works/10.1159%2F000338048

21 January 2018

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

1 reference

https://api.crossref.org/works/10.1159%2F000338048

21 January 2018

Sirtuins: the 'magnificent seven', function, metabolism and longevity

1 reference

https://api.crossref.org/works/10.1159%2F000338048

21 January 2018

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

1 reference

https://api.crossref.org/works/10.1159%2F000338048

21 January 2018

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

1 reference

https://api.crossref.org/works/10.1159%2F000338048

21 January 2018

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

1 reference

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Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

1 reference

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Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease.

1 reference

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Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1.

1 reference

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Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

1 reference

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Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle

1 reference

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Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activity

1 reference

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21 January 2018

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis

1 reference

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21 January 2018

Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1159%2F000338048

21 January 2018

An in vitro screening cascade to identify neuroprotective antioxidants in ALS

1 reference

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21 January 2018

Amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1159%2F000338048

21 January 2018

Identifiers

10.1159/000338048

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

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