(Q45712598)

15 December 2017

title

Cognitive deficit and development of motor impairment in a mouse model of Niemann-Pick type C disease (English)

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15 December 2017

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15 December 2017

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15 December 2017

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Elina Ikonen

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15 December 2017

language of work or name

English

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publication date

1 April 2002

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Behavioural Brain Research

15 December 2017

published in

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15 December 2017

volume

132

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15 December 2017

issue

1

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15 December 2017

page(s)

1-10

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A C57BL/KsJ mouse model of Niemann-Pick disease (spm) belongs to the same complementation group as the major childhood type of Niemann-Pick disease type C.

15 December 2017

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Type-C Niemann-Pick disease: low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes

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Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease

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Cholesterol reutilization during myelination of regenerating PNS axons is impaired in Niemann-Pick disease type C mice

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Gender effect on Purkinje cell loss in the cerebellum of the heterozygous reeler mouse

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Embryonic Striatal Neurons from Niemann-Pick Type C Mice Exhibit Defects in Cholesterol Metabolism and Neurotrophin Responsiveness

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Alleviation of neuronal ganglioside storage does not improve the clinical course of the Niemann-Pick C disease mouse

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Identification of HE1 as the second gene of Niemann-Pick C disease

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Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann- Pick type C disease

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7 January 2021

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7 January 2021

Cholesterol and oxygenated cholesterol concentrations are markedly elevated in peripheral tissue but not in brain from mice with the Niemann-Pick type C phenotype.

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7 January 2021

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7 January 2021

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7 January 2021

Cholesterol is sequestered in the brains of mice with Niemann-Pick type C disease but turnover is increased.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Identifiers

DOI

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15 December 2017

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