(Q45731473)

English

Inhibition of hepatitis C virus NS3 protease by peptides derived from complementarity-determining regions (CDRs) of the monoclonal antibody 8D4: tolerance of a CDR peptide to conformational changes of a target.

scientific article published in August 2002

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11 November 2019

Inhibition of hepatitis C virus NS3 protease by peptides derived from complementarity-determining regions (CDRs) of the monoclonal antibody 8D4: tolerance of a CDR peptide to conformational changes of a target (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163165%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Hepatitis C virus

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based on heuristic

inferred from title

4

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11 November 2019

Hideki Watanabe

7

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11 November 2019

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Kouhei Tsumoto

1

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11 November 2019

Satoru Misawa

2

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11 November 2019

Yoichi Ohba

3

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11 November 2019

Hideya Hayashi

5

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11 November 2019

Nobuhiro Kasai

6

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11 November 2019

Ryutaro Asano

8

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11 November 2019

Izumi Kumagai

9

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11 November 2019

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1 August 2002

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11 November 2019

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11 November 2019

525

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11 November 2019

1-3

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11 November 2019

77-82

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11 November 2019

Interactions of protein antigens with antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Therapeutic peptides and peptidomimetics

1 reference

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21 January 2018

Conformations of immunoglobulin hypervariable regions

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Standard conformations for the canonical structures of immunoglobulins

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Design and synthesis of a mimetic from an antibody complementarity-determining region.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

The mechanism by which a peptide based on complementarity-determining region-1 of a pathogenic anti-DNA auto-Ab ameliorates experimental systemic lupus erythematosus

1 reference

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21 January 2018

A complementarity-determining region synthetic peptide acts as a miniantibody and neutralizes human immunodeficiency virus type 1 in vitro

1 reference

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21 January 2018

Properties and mechanism of action of a 17 amino acid, V3 loop-specific microantibody that binds to and neutralizes human immunodeficiency virus type 1 virions

1 reference

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21 January 2018

Synthetic peptides derived from the variable regions of an anti-CD4 monoclonal antibody bind to CD4 and inhibit HIV-1 promoter activation in virus-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Hepatitis C virus protease inhibitors: current progress and future challenges

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

The NS3/4A proteinase of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Isolation and characterization of monoclonal antibodies that inhibit hepatitis C virus NS3 protease

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Inhibition of the hepatitis C virus NS3 protease activity by Fv fragment of antibody 8D4.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Solution structure and dynamics of the single-chain hepatitis C virus NS3 protease NS4A cofactor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Solution structure of substrate-based ligands when bound to hepatitis C virus NS3 protease domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Hepatitis C virus NS3 protease requires its NS4A cofactor peptide for optimal binding of a boronic acid inhibitor as shown by NMR.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Potent peptide inhibitors of human hepatitis C virus NS3 protease are obtained by optimizing the cleavage products

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

Anatomy of hot spots in protein interfaces

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

21 January 2018

The basics of binding: mechanisms of antigen recognition and mimicry by antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

7 January 2021

Canonical structures for the hypervariable regions of immunoglobulins

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

7 January 2021

Hepatitis C virus NS3/4A protease

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

7 January 2021

Peptide design based on an antibody complementarity-determining region (CDR): construction of porphyrin-binding peptides and their affinity maturation by a combinatorial method

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

7 January 2021

X-ray crystallography of antibodies.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903090-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0014-5793(02)03090-9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163165%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163165%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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