(Q45753289)

15 December 2017

title

Differential role of Rho GTPases in intestinal epithelial barrier regulation in vitro (English)

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15 December 2017

5

Jens Waschke

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15 December 2017

author name string

Nicolas Schlegel

1

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15 December 2017

Michael Meir

2

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Volker Spindler

3

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Christoph-Thomas Germer

4

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publication date

1 May 2011

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15 December 2017

Journal of Cellular Physiology

published in

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15 December 2017

volume

226

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issue

5

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15 December 2017

page(s)

1196-1203

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15 December 2017

Rho GTPases as targets of bacterial protein toxins

cites work

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Selective paracellular permeability in two models of intestinal absorption: cultured monolayers of human intestinal epithelial cells and rat intestinal segments

21 January 2018

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The bacterial virulence factor lymphostatin compromises intestinal epithelial barrier function by modulating rho GTPases

21 January 2018

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Differential role of Rho GTPases in endothelial barrier regulation dependent on endothelial cell origin.

21 January 2018

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Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdown.

21 January 2018

1 reference

Driving Rho GTPase activity in endothelial cells regulates barrier integrity.

21 January 2018

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The cytotoxic necrotizing factors from Yersinia pseudotuberculosis and from Escherichia coli bind to different cellular receptors but take the same route to the cytosol

21 January 2018

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RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin

21 January 2018

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Repetitive deformation activates focal adhesion kinase and ERK mitogenic signals in human Caco-2 intestinal epithelial cells through Src and Rac1.

21 January 2018

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Junctional complexes in various epithelia

21 January 2018

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Molecular decipherment of Rho effector pathways regulating tight-junction permeability

21 January 2018

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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

21 January 2018

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Transcriptional modulation of genes encoding structural characteristics of differentiating enterocytes during development of a polarized epithelium in vitro

21 January 2018

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Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function.

21 January 2018

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Increased colorectal permeability in patients with severe sepsis and septic shock.

21 January 2018

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Coupling between apical and paracellular transport processes

21 January 2018

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Role of the intestinal barrier in inflammatory bowel disease

21 January 2018

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Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia

21 January 2018

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Clostridial glucosylating toxins enter cells via clathrin-mediated endocytosis

21 January 2018

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The gastrointestinal tract as a barrier in sepsis

21 January 2018

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Regulation of epithelial apical junctional complex by Rho family GTPases

21 January 2018

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Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions

21 January 2018

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The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics.

21 January 2018

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Impaired cAMP and Rac 1 signaling contribute to TNF-alpha-induced endothelial barrier breakdown in microvascular endothelium.

21 January 2018

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Impaired integrin-mediated adhesion contributes to reduced barrier properties in VASP-deficient microvascular endothelium

21 January 2018

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VASP is involved in cAMP-mediated Rac 1 activation in microvascular endothelial cells

21 January 2018

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The role of VASP in regulation of cAMP- and Rac 1-mediated endothelial barrier stabilization

21 January 2018

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Lipopolysaccharide-induced endothelial barrier breakdown is cyclic adenosine monophosphate dependent in vivo and in vitro

21 January 2018

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Desmoglein 2-mediated adhesion is required for intestinal epithelial barrier integrity.

21 January 2018

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The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. Cysteine 866 and histidine 881 are essential for enzyme activity

21 January 2018

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Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed

21 January 2018

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Role of GTPases in control of microvascular permeability

21 January 2018

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Role of the gut in multiple organ failure: bacterial translocation and permeability changes

21 January 2018

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Multifunctional strands in tight junctions

21 January 2018

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Show me the pathway! Regulation of paracellular permeability by Na(+)-glucose cotransport

21 January 2018

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Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane

21 January 2018

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Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia.

21 January 2018

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Requirement of Rac activity for maintenance of capillary endothelial barrier properties

21 January 2018

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Inhibition of Rho A activity causes pemphigus skin blistering

21 January 2018

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Molecular and functional analysis of cadherin-based adherens junctions

21 January 2018

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Extracellular adenosine induces apoptosis in Caco-2 human colonic cancer cells by activating caspase-9/-3 via A(2a) adenosine receptors

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.22446

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15 December 2017

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15 December 2017