(Q45758087)

15 December 2017

title

Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease (English)

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15 December 2017

main subject

toll-like receptor

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author

Bertram Müller-Myhsok

13

object named as

Bertram Müller-Myhsok

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15 December 2017

author name string

Helga P Török

1

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15 December 2017

Jürgen Glas

2

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15 December 2017

Ilona Endres

3

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15 December 2017

Laurian Tonenchi

4

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15 December 2017

Molla Y Teshome

5

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15 December 2017

Martin Wetzke

6

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15 December 2017

Wolfram Klein

7

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15 December 2017

Peter Lohse

8

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15 December 2017

Thomas Ochsenkühn

9

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15 December 2017

Matthias Folwaczny

10

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15 December 2017

Burkhard Göke

11

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15 December 2017

Christian Folwaczny

12

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15 December 2017

Stephan Brand

14

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15 December 2017

language of work or name

English

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publication date

19 May 2009

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15 December 2017

The American Journal of Gastroenterology

published in

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15 December 2017

volume

104

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15 December 2017

issue

7

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15 December 2017

page(s)

1723-1733

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15 December 2017

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

cites work

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2

21 January 2018

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Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis

21 January 2018

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https://api.crossref.org/works/10.1038%2FAJG.2009.184

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

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https://api.crossref.org/works/10.1038%2FAJG.2009.184

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

In vivo CpG DNA/toll-like receptor 9 interaction induces regulatory properties in CD4+CD62L+ T cells which prevent intestinal inflammation in the SCID transfer model of colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation

21 January 2018

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Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Crohn's disease is associated with a toll-like receptor-9 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Functional variants of OCTN cation transporter genes are associated with Crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Genetic variation in DLG5 is associated with inflammatory bowel disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FAJG.2009.184

European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FAJG.2009.184

The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants

21 January 2018

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https://api.crossref.org/works/10.1038%2FAJG.2009.184

Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.

21 January 2018

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Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Degranulation of paneth cells via toll-like receptor 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Crohn's disease and the NOD2 gene: a role for paneth cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Anti-interleukin-12 antibody for active Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

TLR9 activation is defective in common variable immune deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

An association study of asthma and total serum immunoglobin E levels for Toll-like receptor polymorphisms in a Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Lack of association of Toll-like receptor 9 gene polymorphism with Behçet's disease in Japanese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Association study of Toll-like receptor 9 gene polymorphism in Korean patients with systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Genetic variation in toll-like receptor 9 and susceptibility to systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case–control disease association studies☆☆This work was supported

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAJG.2009.184

21 January 2018

Identifiers

DOI

10.1038/AJG.2009.184

1 reference

15 December 2017

PubMed ID

19455129

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15 December 2017