(Q45817386)

16 December 2017

title

Ancient origin of the Parkinson disease gene LRRK2. (English)

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16 December 2017

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1

Marín I

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16 December 2017

language of work or name

English

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publication date

4 June 2008

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16 December 2017

number of pages

10

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Journal of Molecular Evolution

inferred from page(s)

published in

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16 December 2017

volume

67

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16 December 2017

issue

1

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16 December 2017

page(s)

41-50

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16 December 2017

Comparative genomics of the RBR family, including the Parkinson's disease-related gene parkin and the genes of the ariadne subfamily

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00239-008-9122-4

Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease*.

21 January 2018

1 reference

12 December 2020

LRRK2: a common pathway for parkinsonism, pathogenesis and prevention?

1 reference

12 December 2020

Comparative genomics and protein domain graph analyses link ubiquitination and RNA metabolism.

1 reference

12 December 2020

LRRK2 in Parkinson's disease: protein domains and functional insights

1 reference

12 December 2020

Corticobasal syndrome and primary progressive aphasia as manifestations of LRRK2 gene mutations

1 reference

12 December 2020

Leucine-rich repeat kinase 2 associates with lipid rafts

1 reference

12 December 2020

The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity

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12 December 2020

The familial Parkinsonism gene LRRK2 regulates neurite process morphology

1 reference

12 December 2020

LRRK2 mutation analysis in Parkinson disease families with evidence of linkage to PARK8.

1 reference

12 December 2020

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1 reference

12 December 2020

Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1.

1 reference

12 December 2020

A new evolutionary paradigm for the Parkinson disease gene DJ-1

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12 December 2020

InterProScan--an integration platform for the signature-recognition methods in InterPro

1 reference

12 December 2020

1 reference

12 December 2020

Leucine-rich repeat kinase 1: a paralog of LRRK2 and a candidate gene for Parkinson's disease

1 reference

12 December 2020

The Parkinson disease gene LRRK2: evolutionary and structural insights

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12 December 2020

Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila.

1 reference

12 December 2020

HHrep: de novo protein repeat detection and the origin of TIM barrels

1 reference

12 December 2020

LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins

1 reference

12 December 2020

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

1 reference

12 December 2020

A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood

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12 December 2020

Prediction of complete gene structures in human genomic DNA

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12 December 2020

Kinase activity of mutant LRRK2 mediates neuronal toxicity

1 reference

12 December 2020

Large-scale taxonomic profiling of eukaryotic model organisms: a comparison of orthologous proteins encoded by the human, fly, nematode, and yeast genomes.

1 reference

12 December 2020

Parkin and relatives: the RBR family of ubiquitin ligases

1 reference

12 December 2020

The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics

1 reference

12 December 2020

MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0

1 reference

12 December 2020

LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain

1 reference

12 December 2020

Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants

1 reference

12 December 2020

Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization

1 reference

12 December 2020

Roc, a Ras/GTPase domain in complex proteins

1 reference

12 December 2020

Topological characteristics of helical repeat proteins

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12 December 2020

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

1 reference

12 December 2020

10.1007/S00239-008-9122-4

Identifiers

DOI

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16 December 2017

Dimensions Publication ID

1035283815

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Fatcat ID

release_ak7cp2rnqvgsjcxsn4mha5tb3q

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Fatcat

https://api.fatcat.wiki/v0/release/ak7cp2rnqvgsjcxsn4mha5tb3q

24 November 2022

mapped directly with Wikidata item

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16 December 2017