(Q45829201)

16 December 2017

title

Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response (English)

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16 December 2017

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Minna Heikkilä

1

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16 December 2017

Annika Pasanen

series ordinal

2

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16 December 2017

Kari I Kivirikko

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3

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16 December 2017

Johanna Myllyharju

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4

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16 December 2017

language of work or name

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10 April 2011

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16 December 2017

Cellular and Molecular Life Sciences

published in

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16 December 2017

volume

68

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16 December 2017

page(s)

3885-3901

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16 December 2017

issue

23

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16 December 2017

https://scigraph.springernature.com/pub.10.1007/s00018-011-0679-5

exact match

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cites work

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Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

21 January 2018

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21 January 2018

Biology of HIF-1alpha

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Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets

21 January 2018

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

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HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

21 January 2018

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A conserved family of prolyl-4-hydroxylases that modify HIF

21 January 2018

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

21 January 2018

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Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

21 January 2018

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HIF prolyl 4-hydroxylases and their potential as drug targets

21 January 2018

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 January 2018

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Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

21 January 2018

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

21 January 2018

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Biology of hypoxia-inducible factor-2alpha in development and disease

21 January 2018

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Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

21 January 2018

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Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts

21 January 2018

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Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha

21 January 2018

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Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

21 January 2018

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Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus

21 January 2018

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Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS

21 January 2018

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Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex

21 January 2018

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Hypoxia-inducible factor (HIF)-3alpha is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2.

21 January 2018

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Binding and regulation of hypoxia-inducible factor-1 by the inhibitory PAS proteins

21 January 2018

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Human HIF-3alpha4 is a dominant-negative regulator of HIF-1 and is down-regulated in renal cell carcinoma

21 January 2018

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The anchoring protein RACK1 links protein kinase Cepsilon to integrin beta chains. Requirements for adhesion and motility

21 January 2018

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The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases

21 January 2018

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The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction

21 January 2018

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

21 January 2018

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Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

21 January 2018

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Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2

21 January 2018

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Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha

21 January 2018

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Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0679-5

Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia

21 January 2018

1 reference

12 December 2020

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha

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12 December 2020

Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha

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12 December 2020

Integration of oxygen signaling at the consensus HRE.

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12 December 2020

10.1007/S00018-011-0679-5

Identifiers

DOI

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16 December 2017

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1 reference

16 December 2017