(Q45861386)

17 December 2017

title

Zinc supplementation augments TGF-β1-dependent regulatory T cell induction (English)

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17 December 2017

Lothar Rink

4

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Ralf Weiskirchen

object named as

Ralf Weiskirchen

series ordinal

3

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author name string

Martina Maywald

series ordinal

1

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17 December 2017

Steffen K Meurer

series ordinal

2

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17 December 2017

publication date

29 October 2016

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17 December 2017

Molecular Nutrition and Food Research

published in

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17 December 2017

volume

61

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17 December 2017

issue

3

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17 December 2017

Development and maintenance of regulatory T cells

cites work

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

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Critical role of IL-2 and TGF-beta in generation, function and stabilization of Foxp3+CD4+ Treg.

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STAT6 Inhibits TGF-beta1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor

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P38 MAP kinase signaling is required for the conversion of CD4+CD25- T cells into iTreg

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IL-10 production by CD4+ effector T cells: a mechanism for self-regulation

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Functional significance of zinc-related signaling pathways in immune cells.

21 January 2018

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Zinc signals and immune function

21 January 2018

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T-lymphocytes: a target for stimulatory and inhibitory effects of zinc ions

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Functions of zinc in signaling, proliferation and differentiation of mammalian cells

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Zinc signals are essential for lipopolysaccharide-induced signal transduction in monocytes

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Zinc signals promote IL-2-dependent proliferation of T cells

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Effects of zinc deficiency on Th1 and Th2 cytokine shifts

21 January 2018

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A Zinc Clasp Structure Tethers Lck to T Cell Coreceptors CD4 and CD8

21 January 2018

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Chronic zinc deficiency in mice disrupted T cell lymphopoiesis and erythropoiesis while B cell lymphopoiesis and myelopoiesis were maintained

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Impact of the discovery of human zinc deficiency on health

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Intracellular free zinc up-regulates IFN-γ and T-bet essential for Th1 differentiation in Con-A stimulated HUT-78 cells

21 January 2018

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Zinc chloride-mediated reduction of apoptosis as an adjunct immunosuppressive modality in cardiac transplantation

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Zinc enhances the number of regulatory T cells in allergen-stimulated cells from atopic subjects.

21 January 2018

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Zinc supplementation induces regulatory T cells by inhibition of Sirt-1 deacetylase in mixed lymphocyte cultures.

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Zinc inhibits interleukin-1-dependent T cell stimulation

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Transforming growth factor-beta regulation of immune responses

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Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10.

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Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

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TGF-beta: a master of all T cell trades

21 January 2018

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Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

21 January 2018

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SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

21 January 2018

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Oral zinc aspartate treats experimental autoimmune encephalomyelitis

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Zinc requirements and the risks and benefits of zinc supplementation

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The biochemical effects of extracellular Zn(2+) and other metal ions are severely affected by their speciation in cell culture media.

21 January 2018

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Induction of regulatory T cells in Th1-/Th17-driven experimental autoimmune encephalomyelitis by zinc administration

21 January 2018

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Rapid temporal control of Foxp3 protein degradation by sirtuin-1.

21 January 2018

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IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

21 January 2018

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Clinical Outlook for Type-1 and FOXP3(+) T Regulatory Cell-Based Therapy

21 January 2018

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Regulatory T cells and immune tolerance

21 January 2018

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Zinc in pharmacological doses suppresses allogeneic reaction without affecting the antigenic response

21 January 2018

1 reference

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Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

TGFbeta signalling in control of T-cell-mediated self-reactivity

21 January 2018

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IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

21 January 2018

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Transforming growth factor beta activation of p44mapk in proliferating cultures of epithelial cells

21 January 2018

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Tgf-beta induced Erk phosphorylation of smad linker region regulates smad signaling

21 January 2018

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TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses

21 January 2018

1 reference

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Repletion of zinc in zinc-deficient cells strongly up-regulates IL-1β-induced IL-2 production in T-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

Phosphorylation of the lymphoid cell kinase p56lck is stimulated by micromolar concentrations of Zn2+.

21 January 2018

1 reference

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A Zn2+ ion links the cytoplasmic tail of CD4 and the N-terminal region of Lck

21 January 2018

1 reference

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Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201600493

The many paths to p38 mitogen-activated protein kinase activation in the immune system

21 January 2018

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Intracellular zinc fluctuations modulate protein tyrosine phosphatase activity in insulin/insulin-like growth factor-1 signaling.

21 January 2018

1 reference

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Protein tyrosine phosphatases as targets of the combined insulinomimetic effects of zinc and oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

Signals and pathways controlling regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

Single-molecule imaging reveals transforming growth factor-beta-induced type II receptor dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

Monomeric type I and type III transforming growth factor-β receptors and their dimerization revealed by single-molecule imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

TbetaRI/Alk5-independent TbetaRII signaling to ERK1/2 in human skin cells according to distinct levels of TbetaRII expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

Zinc oxide influences mitogen-activated protein kinase and TGF-β1 signaling pathways, and enhances intestinal barrier integrity in weaned pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

Cutting Edge: TGF- Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4+CD25+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201600493

21 January 2018

Identifiers

DOI

10.1002/MNFR.201600493

1 reference

17 December 2017

1 reference

17 December 2017