(Q45864162)

17 December 2017

title

Minimal doses of a sequence-optimized transgene mediate high-level and long-term EPO expression in vivo: challenging CpG-free gene design (English)

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17 December 2017

author name string

D Kosovac

1

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17 December 2017

J Wild

2

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17 December 2017

C Ludwig

3

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17 December 2017

S Meissner

4

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17 December 2017

A P Bauer

5

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17 December 2017

R Wagner

6

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17 December 2017

publication date

14 October 2010

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

18

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17 December 2017

issue

2

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17 December 2017

page(s)

189-198

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/gt.2010.134

exact match

0 references

cites work

Nonviral approaches satisfying various requirements for effective in vivo gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Towards safe, non-viral therapeutic gene expression in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Electro-gene-transfer: a new approach for muscle gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Therapy of anemia in kidney failure, using plasmid encoding erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Nonviral gene delivery: principle, limitations, and recent progress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

High-efficiency gene transfer into skeletal muscle mediated by electric pulses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Efficient and regulated erythropoietin production by naked DNA injection and muscle electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Gene transfer into muscle by electroporation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Rational vector design for efficient non-viral gene delivery: challenges facing the use of plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Controlling the kinetics of transgene expression by plasmid design

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Plasmid engineering for controlled and sustained gene expression for nonviral gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Codon optimization for high-level expression of human erythropoietin (EPO) in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Codon bias and heterologous protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Mammalian mutation pressure, synonymous codon choice, and mRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Effects of inflammatory response on in vivo transgene expression by plasmid DNA in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

The role of CpG motifs in immunostimulation and gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Long-term transgene expression from plasmid DNA gene therapy vectors is negatively affected by CpG dinucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

CpG content affects gene silencing in mice: evidence from novel transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Plasmid CpG depletion improves degree and duration of tumor gene expression after intravenous administration of polyplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Gene therapy progress and prospects: recent progress in transgene and RNAi expression cassettes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

The impact of intragenic CpG content on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Methylation of episomal plasmids as a barrier to transient gene expression via a synthetic delivery vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Using skeletal muscle as an artificial endocrine tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Optimization of ectopic gene expression in skeletal muscle through DNA transfer by electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Gene therapy for long-term expression of erythropoietin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Sensitive and precise regulation of haemoglobin after gene transfer of erythropoietin to muscle tissue using electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Progress toward a nonviral gene therapy protocol for the treatment of anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Long-term production of erythropoietin after electroporation-mediated transfer of plasmid DNA into the muscles of normal and uremic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Gene electro-transfer of an improved erythropoietin plasmid in mice and non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Careful adjustment of Epo non-viral gene therapy for beta-thalassemic anaemia treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Gene expression profiles in skeletal muscle after gene electrotransfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Electroporation-facilitated delivery of plasmid DNA in skeletal muscle: plasmid dependence of muscle damage and effect of poloxamer 188.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

In vivo gene electrotransfer into skeletal muscle: effects of plasmid DNA on the occurrence and extent of muscle damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Reducing the immunostimulatory activity of CpG-containing plasmid DNA vectors for non-viral gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Prolonged expression and effective readministration of erythropoietin delivered with a fully deleted adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Autoimmune anemia in macaques following erythropoietin gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Erythropoietin gene therapy leads to autoimmune anemia in macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Advances in high-capacity extrachromosomal vector technology: episomal maintenance, vector delivery, and transgene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

A validated model of in vivo electric field distribution in tissues for electrochemotherapy and for DNA electrotransfer for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Regulated gene expression systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Replication-deficient vaccinia virus encoding bacteriophage T7 RNA polymerase for transient gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

A new mathematical model for relative quantification in real-time RT-PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

Improvement of mouse beta-thalassemia by electrotransfer of erythropoietin cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

CpG-depleted plasmid DNA vectors with enhanced safety and long-term gene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

7 January 2021

Erythropoietin secretion and physiological effect in mouse after intramuscular plasmid DNA electrotransfer

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

7 January 2021

Ligand-regulatable erythropoietin production by plasmid injection and in vivo electroporation

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

7 January 2021

The GeneOptimizer Algorithm: using a sliding window approach to cope with the vast sequence space in multiparameter DNA sequence optimization

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.134

7 January 2021

Identifiers

DOI

10.1038/GT.2010.134

1 reference

17 December 2017

Dimensions Publication ID

1018327559

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Fatcat ID

release_t5qtrmyl7repbnotfjlbqklo3y

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Fatcat

https://api.fatcat.wiki/v0/release/t5qtrmyl7repbnotfjlbqklo3y

24 November 2022

mapped directly with Wikidata item

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17 December 2017