(Q45865603)

17 December 2017

title

Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations (English)

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17 December 2017

juvenile myelomonocytic leukemia

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3

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17 December 2017

author name string

A Metzner

1

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17 December 2017

M A Horstmann

2

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17 December 2017

G Ortmeyer

4

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17 December 2017

C M Niemeyer

5

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17 December 2017

C Stocking

6

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17 December 2017

G W Mayr

7

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17 December 2017

M Jücker

8

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17 December 2017

publication date

1 February 2007

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

14

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17 December 2017

issue

8

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17 December 2017

page(s)

699-703

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17 December 2017

SHIP, a new player in cytokine-induced signalling

cites work

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

Possible dominant-negative mutation of the SHIP gene in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

Hematopoietic stem cell transplantation (HSCT) in children with juvenile myelomonocytic leukemia (JMML): results of the EWOG-MDS/EBMT trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

7 January 2021

SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

7 January 2021

Juvenile Chronic Myelogenous Leukemia Multilineage CD34+Cells: Aberrant Growth and Differentiation Properties

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

7 January 2021

RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

7 January 2021

High-titer packaging cells producing recombinant retroviruses resistant to human serum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

7 January 2021

The use of range in place of standard deviation in the tau-test

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302912

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302912

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17 December 2017

Dimensions Publication ID

1043289426

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17 December 2017