(Q45865772)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17285138%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Pseudo-hydrodynamic delivery of helper-dependent adenoviral vectors into non-human primates for liver-directed gene therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17285138%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

0 references

1 reference

4

1 reference

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25 December 2019

author name string

Nicola Brunetti-Pierri

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17285138%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Gary E Stapleton

2

1 reference

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25 December 2019

Donna J Palmer

3

1 reference

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25 December 2019

Viraj P Mane

5

1 reference

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25 December 2019

Milton J Finegold

6

1 reference

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25 December 2019

Arthur L Beaudet

7

1 reference

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25 December 2019

Michelle M Leland

8

1 reference

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25 December 2019

Charles E Mullins

9

1 reference

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25 December 2019

Philip Ng

10

1 reference

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25 December 2019

publication date

6 February 2007

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25 December 2019

1 reference

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25 December 2019

volume

15

1 reference

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25 December 2019

issue

4

1 reference

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25 December 2019

page(s)

732-740

1 reference

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Liver gene therapy: advances and hurdles

25 December 2019

cites work

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7 January 2021

Helper-dependent adenoviral vectors for gene therapy

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Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector

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Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector

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Sustained phenotypic correction of canine hemophilia B after systemic administration of helper-dependent adenoviral vector

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7 January 2021

Improved hepatic transduction, reduced systemic vector dissemination, and long-term transgene expression by delivering helper-dependent adenoviral vectors into the surgically isolated liver of nonhuman primates.

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7 January 2021

Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons

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7 January 2021

High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity

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7 January 2021

Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver

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7 January 2021

Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors

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7 January 2021

Liver-directed gene transfer in non-human primates

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Gene transfer into the liver of nonhuman primates with E1-deleted recombinant adenoviral vectors: safety of readministration

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7 January 2021

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

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7 January 2021

The innate immune response to adenovirus vectors

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7 January 2021

Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo

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7 January 2021

Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.

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7 January 2021

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

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7 January 2021

Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

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7 January 2021

Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates.

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7 January 2021

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

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7 January 2021

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

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7 January 2021

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

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7 January 2021

Increased hepatic transduction with reduced systemic dissemination and proinflammatory cytokines following hydrodynamic injection of helper-dependent adenoviral vectors.

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7 January 2021

Hydrodynamics-based transfection of the liver: entrance into hepatocytes of DNA that causes expression takes place very early after injection

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7 January 2021

Hydroporation as the mechanism of hydrodynamic delivery

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7 January 2021

The size of sinusoidal fenestrae is a critical determinant of hepatocyte transduction after adenoviral gene transfer

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7 January 2021

Adenovirus endocytosis

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7 January 2021

Expression of naked plasmid DNA injected into the afferent and efferent vessels of rodent and dog livers

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7 January 2021

Development of catheter-based procedures for transducing the isolated rabbit liver with plasmid DNA.

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7 January 2021

Effects of stuffer DNA on transgene expression from helper-dependent adenovirus vectors.

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7 January 2021

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7 January 2021

Variables affecting in vivo performance of high-capacity adenovirus vectors

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7 January 2021

Hemodynamic changes during a new procedure for regional chemotherapy involving occlusion of the thoracic aorta and inferior vena cava.

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7 January 2021

Improved system for helper-dependent adenoviral vector production

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7 January 2021

Physical and infectious titers of helper-dependent adenoviral vectors: a method of direct comparison to the adenovirus reference material

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7 January 2021

"Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung

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7 January 2021

Preexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicity

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7 January 2021