(Q45876565)

17 December 2017

title

Potent antitumoral efficacy of a novel replicative adenovirus CNHK300 targeting telomerase-positive cancer cells (English)

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17 December 2017

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C-Q Su

1

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17 December 2017

J Sham

2

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17 December 2017

H-B Xue

3

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17 December 2017

X-H Wang

4

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17 December 2017

D Chua

5

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17 December 2017

Z-F Cui

6

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17 December 2017

L-H Peng

7

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17 December 2017

L-F Li

8

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17 December 2017

L-H Jiang

9

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17 December 2017

M-C Wu

10

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17 December 2017

Q-J Qian

11

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17 December 2017

publication date

9 July 2004

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17 December 2017

Journal of Cancer Research and Clinical Oncology

published in

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17 December 2017

volume

130

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17 December 2017

issue

10

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17 December 2017

page(s)

591-603

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17 December 2017

https://scigraph.springernature.com/pub.10.1007/s00432-004-0577-4

exact match

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cites work

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Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents

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12 December 2020

Telomerase-dependent oncolytic adenovirus for cancer treatment

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12 December 2020

Telomerase-specific replication-selective virotherapy for human cancer

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12 December 2020

Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT)

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12 December 2020

Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells

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12 December 2020

Molecular targeting of cancer: telomeres as targets

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12 December 2020

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

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12 December 2020

The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

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12 December 2020

A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer

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12 December 2020

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

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12 December 2020

Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers.

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12 December 2020

Telomerase activity in candidate stem cells from fetal liver and adult bone marrow

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12 December 2020

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

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12 December 2020

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

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12 December 2020

Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen.

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12 December 2020

Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT.

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12 December 2020

Specific association of human telomerase activity with immortal cells and cancer

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12 December 2020

An E2F-responsive replication-selective adenovirus targeted to the defective cell cycle in cancer cells: potent antitumoral efficacy but no toxicity to normal cell

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Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells.

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12 December 2020

Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells

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12 December 2020

A novel oncolytic adenovirus targeting to telomerase activity in tumor cells with potent

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12 December 2020

New oncolytic adenoviruses with hypoxia- and estrogen receptor-regulated replication

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12 December 2020

Conditionally replicative adenovirus driven by the human telomerase promoter provides broad-spectrum antitumor activity without liver toxicity

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12 December 2020

p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication

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12 December 2020

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

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12 December 2020

Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression

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12 December 2020

The use of the L-plastin promoter for adenoviral-mediated, tumor-specific gene expression in ovarian and bladder cancer cell lines

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12 December 2020

Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy

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12 December 2020

A survey of telomerase activity in human cancer

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12 December 2020

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.

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12 December 2020

Improvements in methods for calculating virus titer estimates from TCID50 and plaque assays

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12 December 2020

A telomerase-dependent conditionally replicating adenovirus for selective treatment of cancer

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12 December 2020

Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow

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12 December 2020

Activity and expression of human telomerase in normal and malignant cells in gastric and colon cancer patients.

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12 December 2020

hTERT promoter induces tumor-specific Bax gene expression and cell killing in syngenic mouse tumor model and prevents systemic toxicity

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12 December 2020

Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by cell type-specific expression of herpes simplex virus thymidine kinase gene.

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12 December 2020

Telomerase and retrotransposons: which came first?

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12 December 2020

Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells

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12 December 2020

Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1

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12 December 2020

hTERT gene dosage correlates with telomerase activity in human lung cancer cell lines

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12 December 2020

Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene.

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12 December 2020

A novel telomerase-specific gene therapy: gene transfer of caspase-8 utilizing the human telomerase catalytic subunit gene promoter

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12 December 2020

10.1007/S00432-004-0577-4

Identifiers

DOI

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17 December 2017

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17 December 2017