(Q45881054)

17 December 2017

title

Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression (English)

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17 December 2017

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Pipiya T

1

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17 December 2017

Sauthoff H

2

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17 December 2017

Huang YQ

3

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17 December 2017

Chang B

4

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17 December 2017

Cheng J

5

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17 December 2017

Heitner S

6

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17 December 2017

Chen S

7

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17 December 2017

Rom WN

8

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17 December 2017

Hay JG

9

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17 December 2017

publication date

1 June 2005

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

12

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17 December 2017

page(s)

911-917

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17 December 2017

issue

11

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.gt.3302459

exact match

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cites work

Replication-selective adenoviruses as oncolytic agents

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Oncolytic biotherapy: a novel therapeutic plafform

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Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein

21 January 2018

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Intratumoral spread of wild-type adenovirus is limited after local injection of human xenograft tumors: virus persists and spreads systemically at late time points

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Exploiting tumour hypoxia in cancer treatment

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Hypoxia as a target for combined modality treatments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

HIF hydroxylation and cellular oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Anoxic fibroblasts activate a replication checkpoint that is bypassed by E1a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Translation initiation and viral tricks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by the adenovirus 100-kilodalton protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

DNA sequence of the deletion/insertion in early region 3 of Ad5 dl309.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Methods for construction of adenovirus vectors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Deletion of the adenoviral E1b-19kD gene enhances tumor cell killing of a replicating adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

Assessment of adenoviral vector safety and toxicity: report of the National Institutes of Health Recombinant DNA Advisory Committee

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

7 January 2021

Wild-type adenovirus decreases tumor xenograft growth, but despite viral persistence complete tumor responses are rarely achieved--deletion of the viral E1b-19-kD gene increases the viral oncolytic effect

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

7 January 2021

Can NMR diffusion-weighted imaging provide quantitative information on tumor interstital pO2?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

7 January 2021

Hypoxia inhibits G1/S transition through regulation of p27 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

7 January 2021

The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

7 January 2021

Progress in cancer gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302459

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302459

1 reference

17 December 2017

Dimensions Publication ID

0 references

1 reference

17 December 2017