(Q34501934)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

review article

1 reference

title

Hypoxia as a target for combined modality treatments (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Marianne Koritzinsky

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Sandra Nuyts

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

author name string

S A Weppler

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

W Landuyt

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

J Theys

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

R K Chiu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

P Lambin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

publication date

1 January 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Cancer

6 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

volume

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

issue

2

1 reference

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6 December 2019

page(s)

240-257

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

Intratumoral pO2-measurements as predictive assay in the treatment of carcinoma of the uterine cervix

6 December 2019

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7 January 2021

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7 January 2021

Hypoxia-mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression

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7 January 2021

Both increased stability and transcription contribute to the induction of the urokinase plasminogen activator receptor (uPAR) message by hypoxia

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7 January 2021

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7 January 2021

Hypoxia facilitates tumour cell detachment by reducing expression of surface adhesion molecules and adhesion to extracellular matrices without loss of cell viability

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7 January 2021

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Anoxia-induced up-regulation of interleukin-8 in human malignant melanoma. A potential mechanism for high tumor aggressiveness

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7 January 2021

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7 January 2021

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7 January 2021

Hypoxia-induced metastasis of human melanoma cells: involvement of vascular endothelial growth factor-mediated angiogenesis

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

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7 January 2021

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7 January 2021

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

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7 January 2021

Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Prognostic Value of Pretreatment Factors in Patients with Locally Advanced Carcinoma of the Uterine Cervix Treated by Radiotherapy Alone

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The prognostic value of hemoglobin and a decrease in hemoglobin during radiotherapy in laryngeal carcinoma

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T1/T2 glottic cancer managed by external beam radiotherapy: the influence of pretreatment hemoglobin on local control

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Anemia is associated with lower local-regional control and survival after radiation therapy for head and neck cancer: a prospective study.

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Radiation myelitis and survival in the radiotherapy of lung cancer

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7 January 2021

Results of treatment and lessons learned from pathologically staged T4 non-small cell lung cancer

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7 January 2021

The effect of arterial oxygen content on the results of radiation therapy for epidermoid bronchogenic carcinoma

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7 January 2021

Local control of muscle-invasive bladder cancer: preoperative radiotherapy and cystectomy versus cystectomy alone

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7 January 2021

Blood tests and prognosis in bladder carcinomas treated with definitive radiotherapy

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7 January 2021

DNA Analysis in Predicting Survival of Irradiated Patients with Transitional Cell Carcinoma of Bladder

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7 January 2021

Prognostic factors in patients with bladder carcinoma treated with definitive irradiation

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7 January 2021

The influence of initial hemoglobin and blood pressure levels on results of radiation therapy for carcinoma of the prostate

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7 January 2021

The significance of anemia in clinical radiation therapy

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7 January 2021

Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx

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7 January 2021

Extrapolations from laboratory and preclinical studies for the use of carbogen and nicotinamide in radiotherapy

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7 January 2021

Effect of nicotinamide on the microregional heterogeneity of oxygen delivery within a murine tumor

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7 January 2021

Radiosensitization with normobaric oxygen and carbogen

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7 January 2021

Changes in the oxygenation of head and neck tumors during carbogen breathing

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7 January 2021

Reducing acute and chronic hypoxia in tumours by combining nicotinamide with carbogen breathing

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7 January 2021

Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients

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https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

The radiation response of KHT sarcomas following nicotinamide treatment and carbogen breathing

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

The effects of carbogen and nicotinamide on intravascular oxyhaemoglobin saturations in SCCVII and KHT murine tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Carbogen and nicotinamide as radiosensitizers in a murine mammary carcinoma using conventional and accelerated radiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

ARCON--current status: summary of a workshop on preclinical and clinical studies

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Enhancement of tumor perfusion and oxygenation by carbogen and nicotinamide during single- and multifraction irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Accelerated radiotherapy with carbogen and nicotinamide (ARCON) for laryngeal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Clinical outcome and tumour microenvironmental effects of accelerated radiotherapy with carbogen and nicotinamide

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma: hyperbaric oxygen, misonidazole, and accelerated radiotherapy, carbogen, and nicotinamide

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

ARCON: accelerated radiotherapy with carbogen and nicotinamide in head and neck squamous cell carcinomas. The experience of the Co-operative group of radiotherapy of the european organization for research and treatment of cancer (EORTC).

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

ARCON: accelerated radiotherapy with carbogen and nicotinamide in non small cell lung cancer: a phase I/II study by the EORTC.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Accelerated radiotherapy, carbogen, and nicotinamide in glioblastoma multiforme: report of European Organization for Research and Treatment of Cancer trial 22933.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Studies of the pharmacokinetic properties of nimorazole

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

A phase I clinical study of Nimorazole as a hypoxic radiosensitizer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Tirapazamine plus cisplatin versus cisplatin in advanced non-small-cell lung cancer: A report of the international CATAPULT I study group. Cisplatin and Tirapazamine in Subjects with Advanced Previously Untreated Non-Small-Cell Lung Tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

A phase I/II evaluation of tirapazamine administered intravenously concurrent with cisplatin and radiotherapy in women with locally advanced cervical cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

SR 4233 (tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Cisplatin anti-tumour potentiation by tirapazamine results from a hypoxia-dependent cellular sensitization to cisplatin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Potentiation of cisplatin activity by the bioreductive agent tirapazamine

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Tirapazamine with cisplatin in patients with advanced non-small-cell lung cancer: a phase II study

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Phase II study of the combination of the novel bioreductive agent, tirapazamine, with cisplatin in patients with advanced non-small-cell lung cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

An investigation of the molecular basis for the synergistic interaction of tirapazamine and cisplatin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

AQ4N: a new approach to hypoxia-activated cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

AQ4N: an alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Chemotherapeutic tumour targeting using clostridial spores

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Colonisation of Clostridium in the body is restricted to hypoxic and necrotic areas of tumours.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Lipid A mutant Salmonella with suppressed virulence and TNFalpha induction retain tumor-targeting in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvironment

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Specific targeting of cytosine deaminase to solid tumors by engineered Clostridium acetobutylicum.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

The use of radiation-induced bacterial promoters in anaerobic conditions: a means to control gene expression in clostridium-mediated therapy for cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Bifidobacterium longum as a delivery system for cancer gene therapy: selective localization and growth in hypoxic tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Evidence for characteristic vascular patterns in solid tumours: quantitative studies using corrosion casts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Vascular attack as a therapeutic strategy for cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Endothelial-cell proliferation in experimental tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Tumor angiogenesis: therapeutic implications

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

The power of the front page of The New York Times

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Thalidomide is an inhibitor of angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

The effect of thalidomide on experimental tumors and metastases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

An anti-human VEGF monoclonal antibody, MV833, that exhibits potent anti-tumor activity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Requirement of vascular integrin alpha v beta 3 for angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Alpha v integrins as receptors for tumor targeting by circulating ligands.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Inhibition of angiogenesis in vivo by interleukin 12.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Cytokines and soluble cytokine receptor induction after IL-12 administration in cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Vascular Endothelium as the Vulnerable Element in Tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Vinca alkaloids: anti-vascular effects in a murine tumour

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

The use of vascularised spheroids to investigate the action of flavone acetic acid on tumour blood vessels

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: evidence for a vascular mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Antineoplastic agents. 291. Isolation and synthesis of combretastatins A-4, A-5, and A-6(1a)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: effects on radiation therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Vascular targeting of solid tumours: a major 'inverse' volume-response relationship following combretastatin A-4 phosphate treatment of rat rhabdomyosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Gene transfer of antisense hypoxia inducible factor-1 alpha enhances the therapeutic efficacy of cancer immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Suppression of tumor growth through disruption of hypoxia-inducible transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Proteasome inhibition: a new strategy in cancer treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Targeting gene expression to hypoxic tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Enhancement of gene expression under hypoxic conditions using fragments of the human vascular endothelial growth factor and the erythropoietin genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Development of a hypoxia-responsive vector for tumor-specific gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Tumour microcirculation as a target for hyperthermia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

1 reference

7 January 2021

Photodynamic therapy in oncology: mechanisms and clinical use.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

Tumor Infarction in Mice by Antibody-Directed Targeting of Tissue Factor to Tumor Vasculature

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2801%2900361-6

7 January 2021

10.1016/S0959-8049(01)00361-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803141%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference