(Q45883837)

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Intratumoral injection of dendritic cells transduced by an SV40-based vector expressing interleukin-15 induces curative immunity mediated by CD8+ T lymphocytes and NK cells

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

Intratumoral injection of dendritic cells transduced by an SV40-based vector expressing interleukin-15 induces curative immunity mediated by CD8+ T lymphocytes and NK cells (English)

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

Ignacio Melero, MD-PhD

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Ignacio Melero

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17 December 2017

http://europepmc.org/abstract/MED/15921960

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Maria Vera

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

Nerea Razquin

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Europe PubMed Central

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17 December 2017

http://europepmc.org/abstract/MED/15921960

Gloria González-Aseguinolaza

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PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

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1 November 2005

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17 December 2017

http://europepmc.org/abstract/MED/15921960

Molecular Therapy

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PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

12

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

5

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

950-959

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

Intratumoral coinjection of two adenoviruses, one encoding the chemokine IFN-gamma-inducible protein-10 and another encoding IL-12, results in marked antitumoral synergy

1 reference

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Cytokine gene transfer into dendritic cells for cancer treatment

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Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.

1 reference

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Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15.

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Interleukin-12 in anti-tumor immunity and immunotherapy.

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Cancer immunotherapy: a treatment for the masses

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Phase I trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors.

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Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas.

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A new packaging cell line for SV40 vectors that eliminates the generation of T-antigen-positive, replication-competent recombinants

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.03.030

7 January 2021

Simian virus-40 as a gene therapy vector.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.03.030

7 January 2021

Factors influencing the production of recombinant SV40 vectors

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A replication-deficient rSV40 mediates liver-directed gene transfer and a long-term amelioration of jaundice in gunn rats

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In vitro-packaged SV40 pseudovirions as highly efficient vectors for gene transfer.

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Gene delivery to the liver using simian virus 40-derived vectors

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Gene therapy using a simian virus 40-derived vector inhibits the development of in vivo human immunodeficiency virus type 1 infection of severe combined immunodeficiency mice implanted with human fetal thymic and liver tissue.

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7 January 2021

Immune responses against SIV envelope glycoprotein, using recombinant SV40 as a vaccine delivery vector

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7 January 2021

The roles of IFN gamma in protection against tumor development and cancer immunoediting

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Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus coding for interleukin 12.

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7 January 2021

Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12.

1 reference

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7 January 2021

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

1 reference

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7 January 2021

IL-15R alpha expression on CD8+ T cells is dispensable for T cell memory

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.03.030

7 January 2021

Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo

1 reference

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7 January 2021

Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides

1 reference

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7 January 2021

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

1 reference

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7 January 2021

IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

1 reference

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7 January 2021

IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice

1 reference

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7 January 2021

Dendritic cell-derived IL-15 controls the induction of CD8 T cell immune responses

1 reference

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7 January 2021

Immunobiology of dendritic cells

1 reference

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7 January 2021

Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo

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NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells

1 reference

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7 January 2021

Immunotherapy of cancer with dendritic-cell-based vaccines

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Dendritic cell immunotherapy: mapping the way.

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Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12.

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Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-alpha induction pathway

1 reference

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IFN-gamma-independent synergistic effects of IL-12 and IL-15 induce anti-tumor immune responses in syngeneic mice

1 reference

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Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas

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The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product

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Durability of transgene expression and vector integration: recombinant SV40-derived gene therapy vectors

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Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response

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Hepatitis C Virus Structural Proteins Impair Dendritic Cell Maturation and Inhibit In Vivo Induction of Cellular Immune Responses

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In vivo cytotoxic T-lymphocyte induction may take place via CD8 T helper lymphocytes

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ELISPOT assay to measure antigen-specific murine CD8(+) T cell responses

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10.1016/J.YMTHE.2005.03.030

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15921960

ResearchGate publication ID

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