(Q45886514)

17 December 2017

title

Tamoxifen-regulated adenoviral E1A chimeras for the control of tumor selective oncolytic adenovirus replication in vitro and in vivo (English)

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17 December 2017

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I Sipo

1

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17 December 2017

X Wang

2

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17 December 2017

A Hurtado Picó

3

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17 December 2017

L Suckau

4

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17 December 2017

S Weger

5

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17 December 2017

W Poller

6

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17 December 2017

H Fechner

7

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17 December 2017

publication date

1 January 2006

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

13

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17 December 2017

issue

2

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17 December 2017

page(s)

173-186

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17 December 2017

Replicative adenoviruses for cancer therapy

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Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein

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Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy

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A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

21 January 2018

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21 January 2018

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A novel, conditionally replicative adenovirus for the treatment of breast cancer that allows controlled replication of E1a-deleted adenoviral vectors

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Target gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by E1B55k-attenuated adenovirus

21 January 2018

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A novel attenuated replication-competent adenovirus for melanoma therapy

21 January 2018

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21 January 2018

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Telomerase-dependent oncolytic adenovirus for cancer treatment

21 January 2018

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Intratumoral spread of wild-type adenovirus is limited after local injection of human xenograft tumors: virus persists and spreads systemically at late time points

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Viral and nonviral factors causing nonspecific replication of tumor- and tissue-specific promoter-dependent oncolytic adenoviruses

21 January 2018

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A novel tetracycline-controlled transactivator-transrepressor system enables external control of oncolytic adenovirus replication

21 January 2018

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A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor

21 January 2018

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Insights into the molecular biology of the estrogen receptor define novel therapeutic targets for breast cancer

21 January 2018

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Mechanisms governing the accumulation of estrogen receptor alpha in MCF-7 breast cancer cells treated with hydroxytamoxifen and related antiestrogens

21 January 2018

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Steroid-receptor fusion of the human immunodeficiency virus type 1 Rev transactivator: mapping cryptic functions of the arginine-rich motif

21 January 2018

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A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

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Ligand-activated site-specific recombination in mice

21 January 2018

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Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein

21 January 2018

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Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

21 January 2018

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Comparison of the tamoxifen regulated chimeric Cre recombinases MerCreMer and CreMer

21 January 2018

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Inducible site-directed recombination in mouse embryonic stem cells

21 January 2018

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The effects of tamoxifen on the female genital tract

21 January 2018

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Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

21 January 2018

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Multiple functional domains in the adenovirus E1A gene

21 January 2018

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Promoter trans-activation of protooncogenes c-fos and c-myc, but not c-Ha-ras, by products of adenovirus early region 1A

21 January 2018

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The adenoviral transcription factor, E1A 13S, trans-activates the human tumor necrosis factor-alpha promoter

21 January 2018

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Mapping of functional domains in adenovirus E1A proteins

21 January 2018

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Expression of p53, or targeting towards EGFR, enhances the oncolytic potency of conditionally replicative adenovirus against neuroblastoma

21 January 2018

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A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells

21 January 2018

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Antitumoral effect of E1B defective adenoviruses in human malignant cells

21 January 2018

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Mechanisms of tamoxifen-induced apoptosis

21 January 2018

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Selective estrogen receptor modulation: concept and consequences in cancer

21 January 2018

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Upstream enhancer activity in the human surfactant protein B gene is mediated by thyroid transcription factor 1

21 January 2018

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Permanent cell line expressing human factor VIII-related antigen established by hybridization

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302604

'Autoreplication' of the vector genome in recombinant adenoviral vectors with different E1 region deletions and transgenes

21 January 2018

1 reference

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Trans-complementation of vector replication versus Coxsackie-adenovirus-receptor overexpression to improve transgene expression in poorly permissive cancer cells

21 January 2018

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Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers

21 January 2018

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An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

21 January 2018

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7 January 2021

New tools for the construction of replication-competent adenoviral vectors with altered E1A regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302604

7 January 2021

Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302604

7 January 2021

Modulation of cyclin gene expression by adenovirus E1A in a cell line with E1A-dependent conditional proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302604

7 January 2021

Update on adenovirus and its vectors

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302604

7 January 2021

Pharmacokinetics of droloxifene and its metabolites in breast cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302604

7 January 2021

Pharmacologic and biologic properties of droloxifene, a new antiestrogen.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302604

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302604

1 reference

17 December 2017

Dimensions Publication ID

1046706601

0 references

1 reference

17 December 2017