(Q45889268)

17 December 2017

title

A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells (English)

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17 December 2017

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3

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Siobhan O Burns

object named as

Siobhan Burns

8

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Adrian Thrasher

object named as

Adrian J Thrasher

9

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William Vainchenker

11

object named as

William Vainchenker

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17 December 2017

author name string

Aurelie Olivier

1

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Laurence Jeanson-Leh

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17 December 2017

Daniel Compagno

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Johanna Blondeau

5

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Khalil Seye

6

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Sabine Charrier

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Olivier Danos

10

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Anne Galy

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17 December 2017

publication date

15 December 2005

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17 December 2017

published in

Molecular Therapy

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17 December 2017

volume

13

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issue

4

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17 December 2017

page(s)

729-737

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17 December 2017

Mechanisms of WASp-mediated hematologic and immunologic disease.

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The Wiskott-Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF-kappa B (RelA) independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement.

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Autoimmunity in Wiskott-Aldrich syndrome: risk factors, clinical features, and outcome in a single-center cohort of 55 patients

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Functional correction of T cells derived from patients with the Wiskott–Aldrich syndrome (WAS) by transduction with an oncoretroviral vector encoding the WAS protein

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Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction.

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Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein

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Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation

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Restoration of podosomes and chemotaxis in Wiskott-Aldrich syndrome macrophages following induced expression of WASp

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Maturation of DC is associated with changes in motile characteristics and adherence

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A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice.

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Monocytes from Wiskott-Aldrich patients differentiate in functional mature dendritic cells with a defect in CD83 expression

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Macrophages of patients with X-linked thrombocytopenia display an attenuated Wiskott-Aldrich syndrome phenotype

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YMTHE.2005.11.003

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17 December 2017

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17 December 2017