(Q45889454)

17 December 2017

title

Chemosensitivity of human malignant glioma: modulation by p53 gene transfer (English)

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17 December 2017

author

Erich Gulbins

4

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17 December 2017

author name string

M Trepel

1

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17 December 2017

P Groscurth

2

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17 December 2017

U Malipiero

3

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J Dichgans

5

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M Weller

6

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17 December 2017

publication date

1 August 1998

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17 December 2017

Journal of Neuro-Oncology

published in

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17 December 2017

volume

39

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17 December 2017

page(s)

19-32

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17 December 2017

issue

1

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17 December 2017

https://scigraph.springernature.com/pub.10.1023/a:1005910323338

exact match

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cites work

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p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines

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Wild-type p53 regulates its own transcription in a cell-type specific manner

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Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

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P53 and induction of apoptosis as a target for anticancer therapy.

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Hypericin-induced apoptosis of human malignant glioma cells is light-dependent, independent of bcl-2 expression, and does not require wild-type p53.

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p53 mutation, expression, and DNA ploidy in evolving gliomas: evidence for two pathways of progression.

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p53 mutations, O6-alkylguanine DNA alkyltransferase activity, and sensitivity to procarbazine in human brain tumors

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WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

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12 December 2020

Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer.

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12 December 2020

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12 December 2020

In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug.

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12 December 2020

p53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs

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12 December 2020

mdm2 expression is induced by wild type p53 activity

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12 December 2020

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice

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12 December 2020

Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis

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12 December 2020

Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation

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12 December 2020

Clinical implications of the p53 gene

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12 December 2020

Transforming growth factor-beta 2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression

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12 December 2020

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

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12 December 2020

Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis

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12 December 2020

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo

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12 December 2020

p53 is required for radiation-induced apoptosis in mouse thymocytes

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12 December 2020

Breast cancer response to adjuvant chemotherapy in correlation with erbB2 and p53 expression

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12 December 2020

The control of apoptosis and drug resistance in ovarian cancer: influence of p53 and Bcl-2.

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12 December 2020

The basis for current treatment recommendations for malignant gliomas

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12 December 2020

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

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12 December 2020

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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12 December 2020

Single cell monitoring of growth arrest and morphological changes induced by transfer of wild-type p53 alleles to glioblastoma cells

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12 December 2020

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Adenovirus-mediated p53 gene delivery inhibits 9L glioma growth in rats.

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12 December 2020

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12 December 2020

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12 December 2020

Human wild type p53 inhibits cell proliferation and elicits dramatic morphological changes in human glioma cell lines in vitro

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12 December 2020

Expression of the p53 tumour suppressor gene product is a determinant of chemosensitivity.

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

MDM2 protein confers the resistance of a human glioblastoma cell line to cisplatin-induced apoptosis

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12 December 2020

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12 December 2020

Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents

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12 December 2020

Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells

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12 December 2020

c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle

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12 December 2020

Wild-type p53 demonstrates functional dominance in a human colon carcinoma cell line in which it induces reversible growth arrest.

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12 December 2020

In vivo gene therapy with p53 or p21 adenovirus for prostate cancer.

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12 December 2020

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

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12 December 2020

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

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12 December 2020

Management of primary malignant brain tumours

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12 December 2020

Clonal expansion of p53 mutant cells is associated with brain tumour progression

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12 December 2020

p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents.

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12 December 2020

Identifiers

DOI

10.1023/A:1005910323338

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17 December 2017

Dimensions Publication ID

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17 December 2017