(Q45914934)

17 December 2017

title

Functional analysis of pyrimidine biosynthesis enzymes using the anticancer drug 5-fluorouracil in Caenorhabditis elegans. (English)

1 reference

17 December 2017

UMP-CMP kinase;UMP-CMP kinase 2 CELE_F40F8.1

main subject

Caenorhabditis elegans

0 references

1 reference

Orotate phosphoribosyltransferase CELE_R12E2.11

1 reference

UMP-CMP kinase 1 CELE_C29F7.3

1 reference

Orotidine 5'-phosphate decarboxylase CELE_T07C4.1

1 reference

Uridine and thymidine phosphorylase CELE_ZK783.2

1 reference

1 reference

Seongseop Kim

1

1 reference

17 December 2017

Dae-Hun Park

2

1 reference

17 December 2017

Tai Hoon Kim

3

1 reference

17 December 2017

Moogak Hwang

4

1 reference

17 December 2017

Jaegal Shim

5

1 reference

17 December 2017

language of work or name

English

0 references

publication date

23 July 2009

1 reference

17 December 2017

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

FEBS Journal

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17 December 2017

volume

276

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17 December 2017

issue

17

1 reference

17 December 2017

page(s)

4715-4726

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17 December 2017

Disorders of purine and pyrimidine metabolism

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Genetic factors influencing pyrimidine-antagonist chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Fluorouracil: biochemistry and pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Potential for predicting toxicity and response of fluoropyrimidines in patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Homeostatic control of uridine and the role of uridine phosphorylase: a biological and clinical update

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Enhancement of fluorouracil therapy by the manipulation of tissue uridine pools

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Activity and substrate specificity of pyrimidine phosphorylases and their role in fluoropyrimidine sensitivity in colon cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Cloning and expression of human uridine phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Identification of a novel human uridine phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Uridine phosphorylase in breast cancer: a new prognostic factor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Uridine phosphorylase is a potential prognostic factor in patients with oral squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Abnormalities in uridine homeostatic regulation and pyrimidine nucleotide metabolism as a consequence of the deletion of the uridine phosphorylase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

5-Fluorouracil (5-FU) induced apoptosis in gastric cancer cell lines: role of the p53 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Intrinsic activity and stability of bifunctional human UMP synthase and its two separate catalytic domains, orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Rapid gene mapping in Caenorhabditis elegans using a high density polymorphism map

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

In vitro simulation study of individualized chemotherapy in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

Orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase exist as multienzyme complex in human malaria parasite Plasmodium falciparum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

An ion-pairing high-performance liquid chromatographic method for the direct simultaneous determination of nucleotides, deoxynucleotides, nicotinic coenzymes, oxypurines, nucleosides, and bases in perchloric acid cell extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07168.X

10.1111/J.1742-4658.2009.07168.X

21 January 2018

Identifiers

DOI

1 reference

17 December 2017

PubMed ID

19645718

1 reference

17 December 2017