(Q45926508)

17 December 2017

title

Glial activation in the rostroventromedial medulla promotes descending facilitation to mediate inflammatory hypersensitivity. (English)

1 reference

17 December 2017

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Jill Roberts

1

1 reference

17 December 2017

Michael H Ossipov

series ordinal

2

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17 December 2017

Frank Porreca

series ordinal

3

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17 December 2017

language of work or name

English

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publication date

9 July 2009

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17 December 2017

European Journal of Neuroscience

published in

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17 December 2017

volume

30

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17 December 2017

issue

2

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17 December 2017

page(s)

229-241

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17 December 2017

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5693227/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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A comparison of spinal Iba1 and GFAP expression in rodent models of acute and chronic pain

24 May 2018

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The neuropathic pain triad: neurons, immune cells and glia

24 May 2018

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Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine cysteine chemokine ligand 21

24 May 2018

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24 May 2018

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Cellular signalling pathways of spinal pain neuroplasticity as targets for analgesic development

24 May 2018

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The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy

24 May 2018

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Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia

24 May 2018

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Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance

24 May 2018

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Descending modulation of pain

24 May 2018

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Glia: a novel drug discovery target for clinical pain

24 May 2018

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P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

24 May 2018

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Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2

24 May 2018

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In the cellular garden of forking paths: how p38 MAPKs signal for downstream assistance

24 May 2018

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24 May 2018

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24 May 2018

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Glial activation: a driving force for pathological pain

24 May 2018

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Neuronal plasticity: increasing the gain in pain

24 May 2018

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MAP kinase pathways activated by stress: the p38 MAPK pathway

24 May 2018

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Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120.

24 May 2018

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Pain modulation: expectation, opioid analgesia and virtual pain.

24 May 2018

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Supraspinal contributions to hyperalgesia

24 May 2018

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Acute peripheral inflammation induces moderate glial activation and spinal IL-1beta expression that correlates with pain behavior in the rat.

24 May 2018

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Microglial reactions after subcutaneous formalin injection into the rat hind paw.

24 May 2018

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Microglia-specific localisation of a novel calcium binding protein, Iba1

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Reactive astrocytes: cellular and molecular cues to biological function

24 May 2018

1 reference

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Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Lidocaine in the rostroventromedial medulla and the periaqueductal gray attenuates allodynia in neuropathic rats.

24 May 2018

1 reference

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Microglia: a sensor for pathological events in the CNS

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Quantitative assessment of tactile allodynia in the rat paw

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Efficient analysis of experimental observations.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Effects of peripheral inflammation on activation of p38 mitogen-activated protein kinase in the rostral ventromedial medulla.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Activation of p38 MAPK in primary afferent neurons by noxious stimulation and its involvement in the development of thermal hyperalgesia

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Snake venom components enhance pain upon subcutaneous injection: an initial examination of spinal cord mediators

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Systemic administration of CNI-1493, a p38 mitogen-activated protein kinase inhibitor, blocks intrathecal human immunodeficiency virus-1 gp120-induced enhanced pain states in rats

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Enhanced evoked excitatory transmitter release in experimental neuropathy requires descending facilitation.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the mu-opioid receptor.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Relationship between nociceptor activity, peripheral edema, spinal microglial activation and long-term hyperalgesia induced by formalin.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Carrageenan-induced changes in spinal nociception and its modulation by the brain stem

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693227

Activity-induced plasticity in brain stem pain modulatory circuitry after inflammation

15 August 2018

1 reference

12 December 2020

Intrathecal interleukin-1 receptor antagonist in combination with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic pain

1 reference

12 December 2020

The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat

1 reference

12 December 2020

Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury

1 reference

12 December 2020

Mitogen-activated protein kinase and protein kinase A signaling pathways stimulate cholecystokinin transcription via activation of cyclic adenosine 3',5'-monophosphate response element-binding protein

1 reference

12 December 2020

Illness-induced hyperalgesia is mediated by spinal neuropeptides and excitatory amino acids

1 reference

12 December 2020

10.1111/J.1460-9568.2009.06813.X

Identifiers

DOI

1 reference

17 December 2017

PMC publication ID

5693227

1 reference

17 December 2017

PubMed publication ID

19614984

1 reference

17 December 2017