(Q45932252)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19592582%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms (English)

1 reference

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2 February 2020

1 reference

iron deficiency anemia

1 reference

1 reference

2

1 reference

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2 February 2020

Carlos López Otín

9

1 reference

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2 February 2020

Mayka Sánchez

3

1 reference

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2 February 2020

Gloria Velasco

8

1 reference

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2 February 2020

4

Cecilia Garabaya

1 reference

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2 February 2020

author name string

Andrew J Ramsay

1

1 reference

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2 February 2020

María P Sardà

5

1 reference

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2 February 2020

Montserrat Baiget

6

1 reference

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2 February 2020

Angel Remacha

7

1 reference

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2 February 2020

publication date

10 July 2009

1 reference

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2 February 2020

published in

Human Molecular Genetics

1 reference

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2 February 2020

volume

18

1 reference

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2 February 2020

issue

19

1 reference

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2 February 2020

page(s)

3673-3683

1 reference

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Human and mouse proteases: a comparative genomic approach

2 February 2020

cites work

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Hypertension in mice lacking the proatrial natriuretic peptide convertase corin

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Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss

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An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss

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Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins

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Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues

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The type II transmembrane serine protease matriptase-2--identification, structural features, enzymology, expression pattern and potential roles

21 January 2018

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The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

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Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis

21 January 2018

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

21 January 2018

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Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

21 January 2018

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The serine protease TMPRSS6 is required to sense iron deficiency

21 January 2018

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Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

21 January 2018

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A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

21 January 2018

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The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

21 January 2018

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Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

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Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

21 January 2018

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A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron

21 January 2018

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Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency

21 January 2018

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Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin

21 January 2018

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Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron deficiency anemia

21 January 2018

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SIFT: Predicting amino acid changes that affect protein function

21 January 2018

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21 January 2018

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Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain

21 January 2018

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Bovine proenteropeptidase is activated by trypsin, and the specificity of enteropeptidase depends on the heavy chain

21 January 2018

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Functional analysis of the transmembrane domain and activation cleavage of human corin: design and characterization of a soluble corin

21 January 2018

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Identification of domain structures in the propeptide of corin essential for the processing of proatrial natriuretic peptide

21 January 2018

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The Activation of Matriptase Requires Its Noncatalytic Domains, Serine Protease Domain, and Its Cognate Inhibitor

21 January 2018

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N-terminal processing is essential for release of epithin, a mouse type II membrane serine protease

21 January 2018

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Filamin is essential for shedding of the transmembrane serine protease, epithin

21 January 2018

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Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

21 January 2018

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Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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