(Q45942633)

18 December 2017

title

MDP-Induced selective tolerance to TLR4 ligands: impairment in NOD2 mutant Crohn's disease patients. (English)

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18 December 2017

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Elisabet Cantó

1

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18 December 2017

Esther Moga

2

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18 December 2017

Elena Ricart

3

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18 December 2017

Orlando Garcia-Bosch

4

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18 December 2017

Esther Garcia-Planella

5

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18 December 2017

Candido Juarez

6

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18 December 2017

Silvia Vidal

7

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18 December 2017

publication date

1 November 2009

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18 December 2017

Inflammatory Bowel Diseases

published in

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18 December 2017

volume

15

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18 December 2017

issue

11

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18 December 2017

page(s)

1686-1696

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18 December 2017

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NODs: intracellular proteins involved in inflammation and apoptosis

21 January 2018

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NLRs join TLRs as innate sensors of pathogens

21 January 2018

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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

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NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

21 January 2018

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Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

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Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

21 January 2018

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Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

21 January 2018

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Anti-inflammatory cytokines induce lipopolysaccharide tolerance in human monocytes without modifying toll-like receptor 4 membrane expression.

21 January 2018

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Involvement of IRAK-M in peptidoglycan-induced tolerance in macrophages

21 January 2018

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Yersinia V antigen induces both TLR homo- and heterotolerance in an IL-10-involving manner

21 January 2018

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Bacterial lipoprotein-induced self-tolerance and cross-tolerance to LPS are associated with reduced IRAK-1 expression and MyD88-IRAK complex formation

21 January 2018

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Regulatory roles for CD14 and phosphatidylinositol in the signaling via toll-like receptor 4-MD-2.

21 January 2018

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The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

21 January 2018

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Chronic stimulation of Nod2 mediates tolerance to bacterial products

21 January 2018

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Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition

21 January 2018

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Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.

21 January 2018

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Rapid flow cytometric measurement of cytokine-induced phosphorylation pathways [CIPP] in human peripheral blood leukocytes

21 January 2018

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Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events

21 January 2018

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Rapid and simple comparison of messenger RNA levels using real-time PCR.

21 January 2018

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Distinctive response of naïve lymphocytes from cord blood to primary activation via TCR.

21 January 2018

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Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1

21 January 2018

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Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease

21 January 2018

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Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists

21 January 2018

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The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan

21 January 2018

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Toll-like receptor 2 and 4 surface expressions on human monocytes are modulated by interferon-gamma and macrophage colony-stimulating factor

21 January 2018

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Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations

21 January 2018

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TAK1 is a central mediator of NOD2 signaling in epidermal cells

21 January 2018

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Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide

21 January 2018

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Reciprocal cross-talk between Nod2 and TAK1 signaling pathways

21 January 2018

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Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway

21 January 2018

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Combinations of ERK and p38 MAPK inhibitors ablate tumor necrosis factor-alpha (TNF-alpha ) mRNA induction. Evidence for selective destabilization of TNF-alpha transcripts

21 January 2018

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Regulation of tumour necrosis factor alpha mRNA stability by the mitogen-activated protein kinase p38 signalling cascade

21 January 2018

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

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Cloning and characterization of human TNF alpha promoter region

21 January 2018

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The immune response in inflammatory bowel disease

21 January 2018

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Dichotomal role of inhibition of p38 MAPK with SB 203580 in experimental colitis

21 January 2018

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Uncoupling the p38 MAPK kinase in IBD: a double edged sword?

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IBD.21013

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18 December 2017

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18 December 2017