(Q45957471)

18 December 2017

title

Hypomorphic mutation of ZAP70 in human results in a late onset immunodeficiency and no autoimmunity. (English)

1 reference

18 December 2017

author

Capucine Picard

1

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18 December 2017

Frédéric Rieux-Laucat

7

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18 December 2017

Karine Chemin

Karine Chemin

3

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Stéphanie Dogniaux

Stéphanie Dogniaux

2

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Fabienne Mazerolles

Fabienne Mazerolles

6

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Marie-Claude Stolzenberg

Marie-Claude Stolzenberg

8

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Claire Hivroz

Claire Hivroz

13

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Françoise Le Deist

11

Françoise Le Deist

1 reference

18 December 2017

author name string

Zofia Maciorowski

4

1 reference

18 December 2017

Annick Lim

5

1 reference

18 December 2017

Marianne Debre

9

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18 December 2017

Jean-Paul Magny

10

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18 December 2017

Alain Fischer

12

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18 December 2017

language of work or name

English

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publication date

1 July 2009

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18 December 2017

European Journal of Immunology

published in

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18 December 2017

volume

39

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18 December 2017

page(s)

1966-1976

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18 December 2017

issue

7

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18 December 2017

Effect of CD3delta deficiency on maturation of alpha/beta and gamma/delta T-cell lineages in severe combined immunodeficiency

cites work

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Independent mutations of the human CD3-epsilon gene resulting in a T cell receptor/CD3 complex immunodeficiency

21 January 2018

1 reference

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Brief report: primary immunodeficiency caused by mutations in the gene encoding the CD3-gamma subunit of the T-lymphocyte receptor

21 January 2018

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TCR dynamics in human mature T lymphocytes lacking CD3 gamma

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.200939385

Inherited and somatic CD3zeta mutations in a patient with T-cell deficiency

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.200939385

T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Human T cell immunodeficiency: when signal transduction goes wrong

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Human primary immunodeficiency diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Existence of activated and memory CD4+ T cells in peripheral blood and their skin infiltration in CD8 deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Temperature-sensitive ZAP70 mutants degrading through a proteasome-independent pathway. Restoration of a kinase domain mutant by Cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

A LAT mutation that inhibits T cell development yet induces lymphoproliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Induction of T helper type 2 immunity by a point mutation in the LAT adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Herpesvirus saimiri replaces ZAP-70 for CD3- and CD2-mediated T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Signal transduction by lymphocyte antigen receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Positive and negative regulation of T-cell activation by adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Depletion of CD8+ cells in human thymic medulla results in selective immune deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Severe combined immunodeficiency with absence of peripheral blood CD8+ T cells due to ZAP-70 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

T follicular helper (TFH) cells in normal and dysregulated immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Function of CD3 epsilon-mediated signals in T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Studies of patients' thymi aid in the discovery and characterization of immunodeficiency in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Essential role for ZAP-70 in both positive and negative selection of thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

7 January 2021

Differential requirement of ZAP-70 for CD2-mediated activation pathways of mature human T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

7 January 2021

Immunodeficiency diseases. Multiple roles for ZAP-70

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

7 January 2021

Clinical heterogeneity can hamper the diagnosis of patients with ZAP70 deficiency

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

7 January 2021

Signaling through ZAP-70 is required for CXCL12-mediated T-cell transendothelial migration

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

7 January 2021

Immunodeficiency with low expression of the T cell receptor/CD3 complex. Effect on T lymphocyte activation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939385

7 January 2021

Identifiers

DOI

10.1002/EJI.200939385

1 reference

18 December 2017

PubMed ID

19548248

1 reference

18 December 2017