(Q46013425)

English

Analgesic efficacy and safety of the novel p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain following peripheral nerve injury: a double-blind, placebo-controlled study.

scientific article published on 14 December 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

Analgesic efficacy and safety of the novel p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain following peripheral nerve injury: a double-blind, placebo-controlled study. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

neuropathic pain

0 references

peripheral nerve injury

1 reference

based on heuristic

inferred from title

author name string

T Ostenfeld

1

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

A Krishen

2

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

R Y Lai

3

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

J Bullman

4

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

A J Baines

5

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

J Green

6

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

P Anand

7

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

M Kelly

8

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

publication date

14 December 2012

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

European Journal of Pain

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

17

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

6

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

844-857

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling.

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Clinical trial of the p38 MAP kinase inhibitor dilmapimod in neuropathic pain following nerve injury.

1 reference

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21 January 2018

Inhibition of p38 mitogen-activated protein kinase improves nitric oxide-mediated vasodilatation and reduces inflammation in hypercholesterolemia.

1 reference

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21 January 2018

p38(MAPK): stress responses from molecular mechanisms to therapeutics

1 reference

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Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations

1 reference

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21 January 2018

Role of spinal p38alpha and beta MAPK in inflammatory hyperalgesia and spinal COX-2 expression

1 reference

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21 January 2018

Development and preliminary validation of a pain measure specific to neuropathic pain: the Neuropathic Pain Scale

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Inhibition of p38: has the fat lady sung?

1 reference

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21 January 2018

Gabapentin in traumatic nerve injury pain: a randomized, double-blind, placebo-controlled, cross-over, multi-center study

1 reference

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21 January 2018

Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia

1 reference

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21 January 2018

Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons

1 reference

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21 January 2018

Peripheral and central mechanisms of inflammatory pain, with emphasis on MAP kinases

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

p38 MAPK, microglial signaling, and neuropathic pain

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Neuronal plasticity and signal transduction in nociceptive neurons: implications for the initiation and maintenance of pathological pain

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Tibia tumor-induced cancer pain involves spinal p38 mitogen-activated protein kinase activation via TLR4-dependent mechanisms

1 reference

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21 January 2018

An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease.

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Microglial signalling cascades in neurodegenerative disease.

1 reference

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21 January 2018

Pregabalin for the treatment of painful diabetic peripheral neuropathy: a double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Pregabalin reduces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomised, placebo-controlled clinical trial.

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

The p38alpha kinase plays a central role in inflammation

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

p38 pathway kinases as anti-inflammatory drug targets

1 reference

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21 January 2018

Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Role of p38 mitogen activated protein kinase in a model of osteosarcoma-induced pain

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Antinociceptive action of a p38alpha MAPK inhibitor, SD-282, in a diabetic neuropathy model

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Pregabalin in the treatment of post-traumatic peripheral neuropathic pain: a randomized double-blind trial

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

Efficacy and tolerability of twice-daily pregabalin for treating pain and related sleep interference in postherpetic neuralgia: a 13-week, randomized trial

1 reference

https://api.crossref.org/works/10.1002%2FJ.1532-2149.2012.00256.X

21 January 2018

The MOS 36-ltem Short-Form Health Survey (SF-36)

1 reference

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21 January 2018

Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model

1 reference

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21 January 2018

The influence of p38 mitogen-activated protein kinase inhibitor on synthesis of inflammatory cytokine tumor necrosis factor alpha in spinal cord of rats with chronic constriction injury.

1 reference

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21 January 2018

Identifiers

10.1002/J.1532-2149.2012.00256.X

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/23239139

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