(Q46043174)

19 December 2017

title

Novel residues lining the CFTR chloride channel pore identified by functional modification of introduced cysteines (English)

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19 December 2017

2

Paul Linsdell

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19 December 2017

Mohammad Fatehi

1

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19 December 2017

publication date

19 April 2009

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19 December 2017

number of pages

14

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Journal of Membrane Biology

inferred from page(s)

published in

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19 December 2017

volume

228

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19 December 2017

issue

3

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19 December 2017

page(s)

151-164

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19 December 2017

Disulphonic stilbene block of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a mammalian cell line and its regulation by a critical pore residue

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00232-009-9167-3

Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

21 January 2018

1 reference

12 December 2020

Amino acid residues lining the chloride channel of the cystic fibrosis transmembrane conductance regulator.

1 reference

12 December 2020

Atomic model of human cystic fibrosis transmembrane conductance regulator: membrane-spanning domains and coupling interfaces

1 reference

12 December 2020

Molecular determinants of Au(CN)(2)(-) binding and permeability within the cystic fibrosis transmembrane conductance regulator Cl(-) channel pore

1 reference

12 December 2020

Positive charges at the intracellular mouth of the pore regulate anion conduction in the CFTR chloride channel

1 reference

12 December 2020

Identification of a region of strong discrimination in the pore of CFTR.

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12 December 2020

Substituted-cysteine accessibility method

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12 December 2020

Permeation through the CFTR chloride channel

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12 December 2020

Purification and crystallization of the cystic fibrosis transmembrane conductance regulator (CFTR).

1 reference

12 December 2020

Direct comparison of the functional roles played by different transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore

1 reference

12 December 2020

Thiocyanate as a probe of the cystic fibrosis transmembrane conductance regulator chloride channel pore

1 reference

12 December 2020

Adenosine triphosphate-dependent asymmetry of anion permeation in the cystic fibrosis transmembrane conductance regulator chloride channel

1 reference

12 December 2020

Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment.

1 reference

12 December 2020

CFTR: covalent and noncovalent modification suggests a role for fixed charges in anion conduction

1 reference

12 December 2020

Identification of a second blocker binding site at the cytoplasmic mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore.

1 reference

12 December 2020

Characterization of mutations located in exon 18 of the CFTR gene

1 reference

12 December 2020

Mutations in CFTR associated with mild-disease-form Cl- channels with altered pore properties.

1 reference

12 December 2020

Molecular basis for the chloride channel activity of cystic fibrosis transmembrane conductance regulator and the consequences of disease-causing mutations

1 reference

12 December 2020

Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore

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12 December 2020

Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel

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12 December 2020

Structure of a bacterial multidrug ABC transporter

1 reference

12 December 2020

Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore

1 reference

12 December 2020

State-dependent access of anions to the cystic fibrosis transmembrane conductance regulator chloride channel pore

1 reference

12 December 2020

On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore

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12 December 2020

Direct and indirect effects of mutations at the outer mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore.

1 reference

12 December 2020

The ABC protein turned chloride channel whose failure causes cystic fibrosis

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12 December 2020

Multiple inhibitory effects of Au(CN)(2-) ions on cystic fibrosis transmembrane conductance regulator Cl(-) channel currents

1 reference

12 December 2020

Asymmetric structure of the cystic fibrosis transmembrane conductance regulator chloride channel pore suggested by mutagenesis of the twelfth transmembrane region

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12 December 2020

Conformational changes in a pore-lining helix coupled to cystic fibrosis transmembrane conductance regulator channel gating

1 reference

12 December 2020

Relationship between anion binding and anion permeability revealed by mutagenesis within the cystic fibrosis transmembrane conductance regulator chloride channel pore

1 reference

12 December 2020

Location of a common inhibitor binding site in the cytoplasmic vestibule of the cystic fibrosis transmembrane conductance regulator chloride channel pore.

1 reference

12 December 2020

Non-pore lining amino acid side chains influence anion selectivity of the human CFTR Cl- channel expressed in mammalian cell lines

1 reference

12 December 2020

Molecular determinants of anion selectivity in the cystic fibrosis transmembrane conductance regulator chloride channel pore

1 reference

12 December 2020

Structure and function of ABC transporters

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12 December 2020

Heterologous expression systems for study of cystic fibrosis transmembrane conductance regulator.

1 reference

12 December 2020

Molecular determinants and role of an anion binding site in the external mouth of the CFTR chloride channel pore

1 reference

12 December 2020

Interaction between permeation and gating in a putative pore domain mutant in the cystic fibrosis transmembrane conductance regulator

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12 December 2020

Channel-lining residues in the M3 membrane-spanning segment of the cystic fibrosis transmembrane conductance regulator

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12 December 2020

Novel pore-lining residues in CFTR that govern permeation and open-channel block

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12 December 2020

10.1007/S00232-009-9167-3

Identifiers

DOI

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19 December 2017

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19 December 2017