(Q46044258)

19 December 2017

title

GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation (English)

1 reference

19 December 2017

author

Ellen V. Rothenberg

4

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19 December 2017

Jose Alberola-Ila

object named as

Jose Alberola-Ila

5

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Michele K. Anderson

object named as

Michele K Anderson

2

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author name string

Gabriela Hernández-Hoyos

1

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19 December 2017

Chi Wang

3

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19 December 2017

language of work or name

English

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publication date

1 July 2003

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19 December 2017

published in

Immunity

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19 December 2017

volume

19

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19 December 2017

issue

1

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19 December 2017

page(s)

83-94

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19 December 2017

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

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Definition of regulatory network elements for T cell development by perturbation analysis with PU.1 and GATA-3.

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Constitutive expression of PU.1 in fetal hematopoietic progenitors blocks T cell development at the pro-T cell stage

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Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47

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Molecular requirements for lineage commitment in the thymus--antibody-mediated receptor engagements reveal a central role for lck in lineage decisions

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7 January 2021

T-cell development and the CD4-CD8 lineage decision

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Involvement of transcription factors TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus

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Overexpression of AML1 transcription factor drives thymocytes into the CD8 single-positive lineage

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Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus

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Differential induction of helper and killer T cells from isolated CD4+CD8+ thymocytes in suspension culture

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GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells

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Signaling and transcription in T helper development

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Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice.

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Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

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Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

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Transcription factor GATA-3 is required for development of the T-cell lineage

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Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death

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TOX: an HMG box protein implicated in the regulation of thymocyte selection

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7 January 2021

Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs

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Identifiers

DOI

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19 December 2017

release_dlrptg5ykrd2xn3eofdlgobpsu

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/dlrptg5ykrd2xn3eofdlgobpsu

24 November 2022

mapped directly with Wikidata item

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19 December 2017