(Q46082313)

19 December 2017

http://europepmc.org/abstract/MED/23637190

title

Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic neuronal injuries (English)

1 reference

19 December 2017

http://europepmc.org/abstract/MED/23637190

1 reference

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

author name string

Shu Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

Changiz Taghibiglou

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

Kimberly Girling

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

Zhifang Dong

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

Shinn-Zong Lin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

Wei Lee

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

Woei-cherng Shyu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 May 2013

1 reference

19 December 2017

http://europepmc.org/abstract/MED/23637190

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

page(s)

7997-8008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

describes a project that uses

15 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6618960/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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12 December 2020

In vivo protein transduction: delivery of a biologically active protein into the mouse

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12 December 2020

Ischemic cell death in brain neurons

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12 December 2020

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

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12 December 2020

Selfotel in acute ischemic stroke : possible neurotoxic effects of an NMDA antagonist

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12 December 2020

Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors

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12 December 2020

Stabilization and productive positioning roles of the C2 domain of PTEN tumor suppressor.

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12 December 2020

Aptiganel hydrochloride in acute ischemic stroke: a randomized controlled trial

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12 December 2020

Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma

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12 December 2020

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

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Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions

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Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions

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Intravenous administration of bone morphogenetic protein-7 after ischemia improves motor function in stroke rats

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PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

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12 December 2020

PTEN regulates Akt kinase activity in hippocampal neurons and increases their sensitivity to glutamate and apoptosis

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12 December 2020

SHIP-2 and PTEN are expressed and active in vascular smooth muscle cell nuclei, but only SHIP-2 is associated with nuclear speckles

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12 December 2020

Is it time to conclude that NMDA antagonists have failed?

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12 December 2020

Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?

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A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia

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The toxic effect of sodium L-glutamate on the inner layers of the retina.

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The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif

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Evolution of diaschisis in a focal stroke model.

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Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer

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Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN.

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12 December 2020

The role of p53-induced apoptosis in cerebral ischemia: effects of the p53 inhibitor pifithrin alpha

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12 December 2020

alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptor (AMPAR) endocytosis is essential for N-methyl-D-aspartate-induced neuronal apoptosis

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12 December 2020

PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus

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12 December 2020

Nucleophosmin/B23, a nuclear PI(3,4,5)P(3) receptor, mediates the antiapoptotic actions of NGF by inhibiting CAD

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12 December 2020

PTEN enters the nucleus by diffusion

1 reference

12 December 2020

Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis

1 reference

12 December 2020

PTEN Autoregulates Its Expression by Stabilization of p53 in a Phosphatase-Independent Manner

1 reference

12 December 2020

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

1 reference

12 December 2020

Ubiquitination regulates PTEN nuclear import and tumor suppression

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12 December 2020

Essential role for nuclear PTEN in maintaining chromosomal integrity

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12 December 2020

NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo

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12 December 2020

Secretoneurin promotes neuroprotection and neuronal plasticity via the Jak2/Stat3 pathway in murine models of stroke

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12 December 2020

A new penumbra: transitioning from injury into repair after stroke

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Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin

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Role of NMDA receptor-dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries.

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12 December 2020

DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke

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PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression

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12 December 2020

Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models.

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Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

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12 December 2020

Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia

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12 December 2020

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12 December 2020

Regulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTEN.

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12 December 2020

Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the rat.

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12 December 2020

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

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12 December 2020

A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction

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12 December 2020

Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate

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12 December 2020

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

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12 December 2020

Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death.

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12 December 2020

Synaptic activity mediates death of hypoxic neurons

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

12 December 2020

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

12 December 2020

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

12 December 2020

A lateralised grip strength test to evaluate unilateral nigrostriatal lesions in rats

1 reference

12 December 2020

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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12 December 2020

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

1 reference

12 December 2020

10.1523/JNEUROSCI.5661-12.2013

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618960&resulttype=core&format=json