(Q46107910)

19 December 2017

title

Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells (English)

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19 December 2017

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Masayoshi Kobune

1

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19 December 2017

Rishu Takimoto

2

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19 December 2017

Kazuyuki Murase

3

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19 December 2017

Satoshi Iyama

4

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19 December 2017

Tsutomu Sato

5

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19 December 2017

Shohei Kikuchi

6

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19 December 2017

Yutaka Kawano

7

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19 December 2017

Kohji Miyanishi

8

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19 December 2017

Yasushi Sato

9

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19 December 2017

Yoshiro Niitsu

10

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19 December 2017

Junji Kato

11

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19 December 2017

publication date

24 February 2009

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19 December 2017

published in

Cancer Science

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19 December 2017

volume

100

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19 December 2017

issue

5

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19 December 2017

page(s)

948-955

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19 December 2017

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Sonic hedgehog signaling is essential for hair development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Pancreatic cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Medulloblastoma growth inhibition by hedgehog pathway blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-beta2m-/- repopulating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Erythroid differentiation in vitro is blocked by cyclopamine, an inhibitor of hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Adenoviral vector-mediated transfer of the Indian hedgehog gene modulates lymphomyelopoiesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Leukemia stem cells in a genetically defined murine model of blast-crisis CML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Gli-1 expression is associated with lymph node metastasis and tumor progression in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Wnt3/RhoA/ROCK signaling pathway is involved in adhesion-mediated drug resistance of multiple myeloma in an autocrine mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Basal cell carcinomas in mice overexpressing Gli2 in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Gli1 is important for medulloblastoma formation in Ptc1+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Essential role of stromally induced hedgehog signaling in B-cell malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Survival and function of human thymic dendritic cells are dependent on autocrine Hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

The hedgehog pathway inhibitor cyclopamine increases levels of p27, and decreases both expression of IGF-II and activation of Akt in PC-3 prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Dose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

All-trans retinoic acid induces proliferation of an irradiated stem cell supporting stromal cell line AFT024.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Intrinsic retinoic acid receptor alpha-cyclin-dependent kinase-activating kinase signaling involves coordination of the restricted proliferation and granulocytic differentiation of human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

Regulation of hematopoiesis by retinoid signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2009.01111.X

10.1111/J.1349-7006.2009.01111.X

21 January 2018

Identifiers

DOI

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19 December 2017

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19 December 2017