(Q46111557)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238649%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

ABCB1 haplotypes differentially affect the pharmacokinetics of the acid and lactone forms of simvastatin and atorvastatin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238649%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238649%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Jenni E Keskitalo

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238649%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

K J Kurkinen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238649%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

P J Neuvoneni

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238649%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

1 October 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238649%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

22 January 2020

published in

1 reference

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22 January 2020

volume

84

1 reference

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22 January 2020

issue

4

1 reference

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22 January 2020

page(s)

457-461

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238649%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/clpt.2008.25

22 January 2020

exact match

0 references

cites work

Apolipoprotein E genotype affects plasma lipid response to atorvastatin in a gender specific manner

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Interactions of human P-glycoprotein with simvastatin, simvastatin acid, and atorvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

A "silent" polymorphism in the MDR1 gene changes substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Polymorphisms in the multidrug resistance-1 (MDR1) gene influence the response to atorvastatin treatment in a gender-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

An association study of 43 SNPs in 16 candidate genes with atorvastatin response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Exposure of atorvastatin is unchanged but lactone and acid metabolites are increased several-fold in patients with atorvastatin-induced myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Effect of itraconazole on the pharmacokinetics and pharmacodynamics of fexofenadine in relation to the MDR1 genetic polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

A New Statistical Method for Haplotype Reconstruction from Population Data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

A comparison of bayesian methods for haplotype reconstruction from population genotype data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Lipid-lowering response to statins is affected by CYP3A5 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

The interconversion kinetics, equilibrium, and solubilities of the lactone and hydroxyacid forms of the HMG-CoA reductase inhibitor, CI-981

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

7 January 2021

Effect of itraconazole on the pharmacokinetics of atorvastatin

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

7 January 2021

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

7 January 2021

Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1 polymorphisms

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

7 January 2021

Quantitation of simvastatin and its beta-hydroxy acid in human plasma by liquid-liquid cartridge extraction and liquid chromatography/tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

7 January 2021

Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2008.25

7 January 2021

Identifiers

DOI

10.1038/CLPT.2008.25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19238649%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 January 2020

1042309181

0 references

1 reference