(Q46120920)

19 December 2017

title

Unsaturated Mannich bases active against multidrug-resistant Trypanosoma brucei brucei strains (English)

1 reference

19 December 2017

main subject

Trypanosoma brucei

0 references

multiple drug resistance

1 reference

Elisabeth Davioud-Charvet

inferred from title

author

7

1 reference

19 December 2017

Michael P. Barrett

6

object named as

Michael P Barrett

0 references

author name string

I Nicole Wenzel

1

1 reference

19 December 2017

Pui E Wong

2

1 reference

19 December 2017

Louis Maes

3

1 reference

19 December 2017

Thomas J J Müller

4

1 reference

19 December 2017

R Luise Krauth-Siegel

5

1 reference

19 December 2017

Michael P Barrett

6

1 reference

19 December 2017

publication date

1 March 2009

1 reference

19 December 2017

published in

ChemMedChem

1 reference

19 December 2017

volume

4

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19 December 2017

issue

3

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19 December 2017

page(s)

339-351

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19 December 2017

Cation-pi bonding and amino-aromatic interactions in the biomolecular recognition of substituted ammonium ligands

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

Dithiol proteins as guardians of the intracellular redox milieu in parasites: old and new drug targets in trypanosomes and malaria-causing plasmodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Mechanism of inhibition of trypanothione reductase and glutathione reductase by trivalent organic arsenicals

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Arsenical-resistant trypanosomes lack an unusual adenosine transporter

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamidine drugs in African trypanosomes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Roles for the Trypanosoma brucei P2 transporter in DB75 uptake and resistance

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

The biochemical basis of arsenical-diamidine crossresistance in African trypanosomes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Drug transport and drug resistance in African trypanosomes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Targeting of toxic compounds to the trypanosome's interior

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

A nucleoside transporter from Trypanosoma brucei involved in drug resistance.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

An approach to use an unusual adenosine transporter to selectively deliver polyamine analogues to trypanosomes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Uptake of pentamidine in Trypanosoma brucei brucei is mediated by the P2 adenosine transporter and at least one novel, unrelated transporter

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

The effect of fluorine substitution on the metabolism and antimalarial activity of amodiaquine.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Trypanocidal activity of melamine-based nitroheterocycles

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Interaction of monobenzamidine-linked trypanocides with the Trypanosoma brucei P2 aminopurine transporter

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

A new type of high affinity folic acid transporter in the protozoan parasite Leishmania and deletion of its gene in methotrexate-resistant cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Silencing of the thioredoxin gene in Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800360

7 January 2021

Identifiers

DOI

10.1002/CMDC.200800360

1 reference

19 December 2017

PubMed ID

19219843

1 reference

19 December 2017