(Q46171322)

http://europepmc.org/abstract/PMC/5776014

20 February 2018

title

Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer (English)

1 reference

http://europepmc.org/abstract/PMC/5776014

20 February 2018

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Marie Wislez

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Jing Shan Lim

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Marcus M Fischer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Belinda Cancilla

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Gilbert O'Young

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Sandra Cristea

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Vincent C Luca

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Dian Yang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Nadine S Jahchan

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Cécile Hamard

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Martine Antoine

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Christina Kong

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jennifer Cain

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Yu-Wang Liu

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Ann M Kapoun

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

K Christopher Garcia

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Timothy Hoey

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Christopher L Murriel

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Julien Sage

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

10 May 2017

1 reference

http://europepmc.org/abstract/PMC/5776014

20 February 2018

published in

Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

545

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

7654

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

360-364

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

9 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5776014/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5776014

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nature22323

0 references

cites work

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24 May 2018

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Cisplatin combined with irinotecan or etoposide for untreated extensive-stage small cell lung cancer: A multicenter randomized controlled clinical trial

24 May 2018

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Notch signaling regulates gastric antral LGR5 stem cell function.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

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24 May 2018

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24 May 2018

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Structural biology. Structural basis for Notch1 engagement of Delta-like 4

24 May 2018

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Improved vectors and genome-wide libraries for CRISPR screening

24 May 2018

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From fly wings to targeted cancer therapies: a centennial for notch signaling

24 May 2018

1 reference

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A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal

24 May 2018

1 reference

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Notch signaling at a glance

24 May 2018

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24 May 2018

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Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells

24 May 2018

1 reference

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Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice

24 May 2018

1 reference

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A crucial requirement for Hedgehog signaling in small cell lung cancer

24 May 2018

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OASIS: online application for the survival analysis of lifespan assays performed in aging research

24 May 2018

1 reference

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A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer

24 May 2018

1 reference

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ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67

24 May 2018

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Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma

24 May 2018

1 reference

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Therapeutic antibody targeting of individual Notch receptors

24 May 2018

1 reference

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Hallmarks of cancer: interactions with the tumor stroma.

24 May 2018

1 reference

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A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Notch signaling controls the balance of ciliated and secretory cell fates in developing airways

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Regulated expression of a tumor-associated antigen reveals multiple levels of T-cell tolerance in a mouse model of lung cancer

24 May 2018

1 reference

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Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Notch and cancer: a double-edged sword

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes

24 May 2018

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

24 May 2018

1 reference

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The many faces of REST oversee epigenetic programming of neuronal genes

24 May 2018

1 reference

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Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Achaete-scute homolog-1 and Notch in lung neuroendocrine development and cancer

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Midkine and pleiotrophin in neural development and cancer

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Annotating the human proteome: the Human Proteome Survey Database (HumanPSD) and an in-depth target database for G protein-coupled receptors (GPCR-PD) from Incyte Genomics

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Notch signaling induces cell cycle arrest in small cell lung cancer cells

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Attenuation of green fluorescent protein half-life in mammalian cells

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

An achaete-scute homologue essential for neuroendocrine differentiation in the lung

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

A common silencer element in the SCG10 and type II Na+ channel genes binds a factor present in nonneuronal cells but not in neuronal cells

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

NRSF causes cAMP-sensitive suppression of sodium current in cultured hippocampal neurons

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5776014

Trophic interactions between astroglial cells and hippocampal neurons in culture

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE22323

7 January 2021

inferred from DOI database lookup

Carboplatin in the Treatment of Small Cell Lung Cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28489825

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NATURE22323

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28489825%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference