(Q46189468)

20 December 2017

title

The essential role of p53 in hyperpigmentation of the skin via regulation of paracrine melanogenic cytokine receptor signaling (English)

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20 December 2017

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Daiki Murase

1

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20 December 2017

Akira Hachiya

2

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20 December 2017

Yasuko Amano

3

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20 December 2017

Atsushi Ohuchi

4

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20 December 2017

Takashi Kitahara

5

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20 December 2017

Yoshinori Takema

6

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20 December 2017

language of work or name

English

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publication date

18 December 2008

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20 December 2017

Journal of Biological Chemistry

published in

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20 December 2017

volume

284

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20 December 2017

issue

7

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20 December 2017

page(s)

4343-4353

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20 December 2017

Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.

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Intracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptor

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Proopiomelanocortin-derived peptides are synthesized and released by human keratinocytes

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Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides

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Increased expression of inducible nitric oxide synthase in psoriatic skin and cytokine-stimulated cultured keratinocytes.

21 January 2018

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Nitric oxide produced by ultraviolet-irradiated keratinocytes stimulates melanogenesis

21 January 2018

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Biphasic expression of two paracrine melanogenic cytokines, stem cell factor and endothelin-1, in ultraviolet B-induced human melanogenesis

21 January 2018

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Keratinocyte-melanocyte interactions during melanosome transfer

21 January 2018

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The role of the epidermal endothelin cascade in the hyperpigmentation mechanism of lentigo senilis

21 January 2018

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The epidermal stem cell factor is over-expressed in lentigo senilis: implication for the mechanism of hyperpigmentation

21 January 2018

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Role of endothelin-1 in hyperpigmentation in seborrhoeic keratosis

21 January 2018

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The mechanism of epidermal hyperpigmentation in dermatofibroma is associated with stem cell factor and hepatocyte growth factor expression

21 January 2018

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The SCF/KIT pathway plays a critical role in the control of normal human melanocyte homeostasis

21 January 2018

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Central role of p53 in the suntan response and pathologic hyperpigmentation

21 January 2018

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Serum-free serial culture of adult human keratinocytes from suction-blister roof epidermis

21 January 2018

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WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

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21 January 2018

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Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway

21 January 2018

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

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Disruption of p53 in human cancer cells alters the responses to therapeutic agents

21 January 2018

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Regulation of p53 stability and function in HCT116 colon cancer cells

21 January 2018

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

21 January 2018

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21 January 2018

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Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis

21 January 2018

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Effect of constitutional pigmentation on ultraviolet B-induced DNA damage in fair-skinned people.

21 January 2018

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Significance of the melanocortin 1 receptor in regulating human melanocyte pigmentation, proliferation, and survival

21 January 2018

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Genetics of Hair and Skin Color

21 January 2018

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Phosphorylation site interdependence of human p53 post-translational modifications in response to stress

21 January 2018

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Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

21 January 2018

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

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Mutation of phosphoserine 389 affects p53 function in vivo

21 January 2018

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Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases

21 January 2018

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Ultraviolet-B-Induced Apoptosis of Keratinocytes: Evidence for Partial Involvement of Tumor Necrosis Factor-α in the Formation of Sunburn Cells

21 January 2018

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Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning

21 January 2018

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Mechanisms of ultraviolet light-induced pigmentation

21 January 2018

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UV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1)

21 January 2018

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A global map of p53 transcription-factor binding sites in the human genome

21 January 2018

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Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

21 January 2018

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p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis.

21 January 2018

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Different cis-acting elements are involved in the regulation of TRP1 and TRP2 promoter activities by cyclic AMP: pivotal role of M boxes (GTCATGTGCT) and of microphthalmia

21 January 2018

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Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication

21 January 2018

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Definition of a consensus binding site for p53

21 January 2018

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Tumor suppressor p53 down-regulates tissue-specific expression of tyrosinase gene in human melanoma cell lines

21 January 2018

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Tyrosinase gene expression is regulated by p53.

21 January 2018

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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

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Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M805570200

Endothelin-1 as a New Melanogen: Coordinated Expression of Its Gene and the Tyrosinase Gene in UVB-Exposed Human Epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805570200

The Role of Endothelin-1 in Epidermal Hyperpigmentation and Signaling Mechanisms of Mitogenesis and Melanogenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M805570200

Sunburn and p53 in the onset of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805570200

21 January 2018

Identifiers

DOI

10.1074/JBC.M805570200

1 reference

20 December 2017

1 reference

20 December 2017