(Q46234268)

20 December 2017

title

Impaired performance of female APP/PS1 mice in the Morris water maze is coupled with increased Aβ accumulation and microglial activation (English)

1 reference

20 December 2017

1 reference

3

1 reference

20 December 2017

author name string

Gallagher JJ

series ordinal

1

1 reference

20 December 2017

Minogue AM

series ordinal

2

1 reference

20 December 2017

publication date

24 May 2012

1 reference

20 December 2017

Neurodegenerative Diseases

published in

1 reference

20 December 2017

volume

11

1 reference

20 December 2017

issue

1

1 reference

20 December 2017

page(s)

33-41

1 reference

20 December 2017

In-vivo measurement of activated microglia in dementia

cites work

1 reference

The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease

21 January 2018

1 reference

NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease.

21 January 2018

1 reference

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

21 January 2018

1 reference

Cytokine indices in Alzheimer's temporal cortex: no changes in mature IL-1 beta or IL-1RA but increases in the associated acute phase proteins IL-6, alpha 2-macroglobulin and C-reactive protein.

21 January 2018

1 reference

Altered plasma cytokine levels in Alzheimer's disease: correlation with the disease progression.

21 January 2018

1 reference

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

21 January 2018

1 reference

Scavenging of Alzheimer's amyloid beta-protein by microglia in culture.

21 January 2018

1 reference

Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease.

21 January 2018

1 reference

Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy.

21 January 2018

1 reference

Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain.

21 January 2018

1 reference

Human neprilysin is capable of degrading amyloid beta peptide not only in the monomeric form but also the pathological oligomeric form

21 January 2018

1 reference

In vitro and in vivo degradation of Abeta peptide by peptidases coupled to erythrocytes

21 January 2018

1 reference

Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases

21 January 2018

1 reference

Metabolic regulation of brain Abeta by neprilysin.

21 January 2018

1 reference

Neprilysin protects neurons against Abeta peptide toxicity

21 January 2018

1 reference

Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

21 January 2018

1 reference

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.

21 January 2018

1 reference

Amyloidogenic determinant as a substrate recognition motif of insulin-degrading enzyme.

21 January 2018

1 reference

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

1 reference

Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia

21 January 2018

1 reference

Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset.

21 January 2018

1 reference

Prevalence of AD among whites: a summary by levels of severity

21 January 2018

1 reference

Why women have more Alzheimer's disease than men: gender and mitochondrial toxicity of amyloid-beta peptide.

21 January 2018

1 reference

Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.

21 January 2018

1 reference

Gender differences in the amount and deposition of amyloidbeta in APPswe and PS1 double transgenic mice

21 January 2018

1 reference

Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology.

21 January 2018

1 reference

Gender- and age-dependent gamma-secretase activity in mouse brain and its implication in sporadic Alzheimer disease

21 January 2018

1 reference

Gender dependent APP processing in a transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

Abeta-degrading enzymes in Alzheimer's disease.

21 January 2018

1 reference

Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide.

21 January 2018

1 reference

The multifaceted profile of activated microglia.

21 January 2018

1 reference

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

21 January 2018

1 reference

Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.

21 January 2018

1 reference

Immunology and immunotherapy of Alzheimer's disease

21 January 2018

1 reference

Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology

21 January 2018

1 reference

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

Inflammation occurs early during the Abeta deposition process in TgCRND8 mice

21 January 2018

1 reference

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

21 January 2018

1 reference

Hippocampal A beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice.

21 January 2018

1 reference

Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease.

21 January 2018

1 reference

Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern

21 January 2018

1 reference

Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice

21 January 2018

1 reference

Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000337458

1 reference

20 December 2017

PubMed ID

22627185

1 reference

20 December 2017