(Q46236280)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Formation of highly toxic soluble amyloid beta oligomers by the molecular chaperone prefoldin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Hiroshi Ueda

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Masafumi Yohda

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Tamotsu Zako

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Mizuo Maeda

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

1 December 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

5982-5993

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19021772%20AND%20SRC:MED&resulttype=core&format=json

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

17 January 2020

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21 January 2018

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Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

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A beta oligomers - a decade of discovery

21 January 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

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A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

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Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 January 2018

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

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Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

21 January 2018

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

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Intracellular amyloid-beta in Alzheimer's disease

21 January 2018

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Intracellular A-beta amyloid, a sign for worse things to come?

21 January 2018

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Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

21 January 2018

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Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed beta-amyloid in neurons.

21 January 2018

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A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade

21 January 2018

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Amyloid peptide attenuates the proteasome activity in neuronal cells

21 January 2018

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Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system.

21 January 2018

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Abeta inhibits the proteasome and enhances amyloid and tau accumulation

21 January 2018

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Molecular chaperones in the cytosol: from nascent chain to folded protein

21 January 2018

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Molecular chaperones and protein quality control

21 January 2018

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Modulation of neurodegeneration by molecular chaperones

21 January 2018

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Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro.

21 January 2018

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Hsp20, a novel alpha-crystallin, prevents Abeta fibril formation and toxicity.

21 January 2018

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Clusterin (apoJ) Alters the Aggregation of Amyloid β-Peptide (Aβ1-42) and Forms Slowly Sedimenting Aβ Complexes That Cause Oxidative Stress

21 January 2018

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Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

21 January 2018

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Prefoldin-nascent chain complexes in the folding of cytoskeletal proteins

21 January 2018

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Compartmentation of protein folding in vivo: sequestration of non-native polypeptide by the chaperonin-GimC system

21 January 2018

1 reference

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Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin

21 January 2018

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Kinetics and binding sites for interaction of the prefoldin with a group II chaperonin: contiguous non-native substrate and chaperonin binding sites in the archaeal prefoldin.

21 January 2018

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Molecular clamp mechanism of substrate binding by hydrophobic coiled-coil residues of the archaeal chaperone prefoldin

21 January 2018

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Facilitated release of substrate protein from prefoldin by chaperonin.

21 January 2018

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Localization of prefoldin interaction sites in the hyperthermophilic group II chaperonin and correlations between binding rate and protein transfer rate.

21 January 2018

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Pyrococcus prefoldin stabilizes protein-folding intermediates and transfers them to chaperonins for correct folding

21 January 2018

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Structure of the molecular chaperone prefoldin: unique interaction of multiple coiled coil tentacles with unfolded proteins

21 January 2018

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Structure of eukaryotic prefoldin and of its complexes with unfolded actin and the cytosolic chaperonin CCT.

21 January 2018

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MtGimC, a novel archaeal chaperone related to the eukaryotic chaperonin cofactor GimC/prefoldin

21 January 2018

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Cloning and characterization of a novel human prefoldin and SPEC domain protein gene (PFD6L) from the fetal brain

21 January 2018

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Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

21 January 2018

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Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct

21 January 2018

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Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

21 January 2018

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21 January 2018

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Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

21 January 2018

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The molecular chaperone alphaB-crystallin enhances amyloid beta neurotoxicity.

21 January 2018

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Binding of amyloid beta-protein to intracellular brain proteins in rat and human.

21 January 2018

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Structure and molecular dynamics simulation of archaeal prefoldin: the molecular mechanism for binding and recognition of nonnative substrate proteins

21 January 2018

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Prefoldin recognition motifs in the nonhomologous proteins of the actin and tubulin families

21 January 2018

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Divergent Substrate-Binding Mechanisms Reveal an Evolutionary Specialization of Eukaryotic Prefoldin Compared to Its Archaeal Counterpart

21 January 2018

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Functional characterization of recombinant prefoldin complexes from a hyperthermophilic archaeon, Thermococcus sp. strain KS-1

21 January 2018

1 reference

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